Senior Scientist I, R&D Diagnostics

Brisbane, CA
May 15, 2022
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Mammoth is seeking a Senior Scientist I, R&D Diagnostics to drive discovery of new DETECTR® in vitro diagnostics. The successful candidate will use their experience with genomic, molecular and biochemical techniques to contribute directly to establishment of novel CRISPR-based in vitro diagnostic assays. 
  • Explore and innovate novel technologies from proof of concept through verification
  • Ideate to develop and improve sample-to-answer CRISPR diagnostic assays and substantiate through clinical utility studies
  • Participate in validation studies and transfer successful new products to development following design control processes
  • Maintain experimental records, perform data analysis and generate summaries for internal and external meetings
  • Resolve problems by examining and evaluating data and selecting corrective steps
  • Stay current in the field by participating in educational opportunities and reading relevant publications

  • PhD in molecular biology, biochemistry, genomics or associated field
  • 3 years of industry experience or 1 year with a Postdoc
  • Hands-on experience with in vitro diagnostic assays
  • Strong background in assay innovation and optimization
  • Experience in R, Python, JMP, and/or other statistical and analysis tools

  • Experience working with CRISPR nucleases 
  • Experience evaluating clinical samples
  • Expertise in genomics and molecular biology, including principles of nucleic acid chemistry, primer design, technologies for gene target amplification using isothermal amplification methods and guide RNA design
  • Working knowledge of design of experiments methodologies
  • Exceptional skills in communication, presentation, data analysis, and interpretation
  • Highly motivated and detail-oriented with the ability to think creatively towards efficient problem solving

  • Company-paid health/vision/dental benefits
  • Unlimited vacation and generous sick time
  • Company-sponsored meals and snacks
  • Wellness, caregiver and ergonomics benefits
  • 401(k) with company matching

Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber.

The Diagnostics team is advancing our CRISPR-based DETECTR® platform to address unmet needs across the continuum of testing. From laboratories to the home, our mission is to democratize diagnostics with CRISPR. 

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Mammoth Biosciences requires that all employees be vaccinated against Covid-19 as a condition of at-will employment, with exceptions for medical or religious reasons in compliance with local, state, and federal law.