Research Associate, Genomics Methods Development

Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We wantall ofour people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia:

We are looking to hire a Research Associate to the growing Genomic Innovation team! As a Research Associate, you will help develop and evaluate new next generation sequencing (NGS) and long read sequencing methods to characterize off-target CRISPR/Cas9 activity and address emerging research questions. You will also apply established high throughput NGS methods help support the characterization and quantitation of unintended off-target genome editing with CRISPR/Cas9. You will work on various oncology and genetic disease areas across different stages of therapeutic development. Additional responsibilities include:

• Apply molecular biology techniques such as DNA purification, shearing, adapter ligation, PCR, NGS library purification and quantification
• Work with other members of the team on development of creative design for new assays and implement testing and development of those assays in the lab
• Evaluate, develop, and conduct genome-wide off-target experiments to characterize guides for therapeutic development
• Troubleshoot and optimize NGS and long-read assays in collaboration with colleagues
• Perform sample processing and library construction for exploratory single cell RNA-Sequencing projects.
• Accurately document project and sample information, protocols, and experimental details through the Laboratory Information Management System (LIMS) and Electronic Lab Notebook (ELN)

About you:

We are looking for a candidate with a BS in Molecular Biology, Biochemistry or a related discipline, with some relevant lab work experience such as an internship, co-op or previous work experience at a biotech/pharma company or in a university research lab. Applicants should have a passion for lab work and strong interest in genomics and gene editing. Candidates must have enthusiasm to learn and grow and the ability to work as part of a cross-functional team.

Candidates should have hands on experience with two or more of the following: PCR, gel electrophoresis, sequencing (Sanger, Illumina NGS, PacBio, and/or Oxford nanopore), bead-based clean-up, DNA/RNA purification, nuclei isolation, cell culture or genome editing with CRISPR/Cas9.

Covid-19 Vaccination Policy: All Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. This requirement includes a booster dose once eligible. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.