Principal Programmer / Director - Health Economics and Outcomes Research Menlo Park CA/Remote#1834

Menlo Park, CA
May 11, 2022
Required Education
Masters Degree/MBA
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

GRAIL’s multi-cancer early detection (MCED) test is now available in the US market. This position will be responsible for providing critical support to the Health Economics and Outcomes Research (HEOR) team for gathering, analyzing, and interpreting real-world databases to assess the potential impact of MCED on patients and the healthcare system. 

The Health Economics Director, working closely with a diverse cross-functional team, will participate in designing and performing studies analyzing real-world databases (e.g. Medicare, SEER, MEPS, Medicaid, commercial claims datasets) on the burden of cancer and the potential impacts of MCED.

You will...
  • Help design projects analyzing health services and cancer epidemiology datasetsDevelop statistical analysis plans and conduct analysesInterpret and summarize key outcomes from the analyses, preferably including visualization Support identification of appropriate datasets for questions of interestSupport ad hoc analyses of proprietary datasets where requested by the cross-functional teamProvide input into HEOR-related strategy for evidence generationSupport HEOR publications (i.e., abstracts, congress presentations, manuscript development) 

Your background should include...
  • PhD in relevant discipline (e.g. statistics, public health, economics, epidemiology); or MS with experience conducting HEOR data analyses
  • 5+ years of professional experiences  in conducting database analyses, or a similar field to support HEOR studies
  • Experienced in programming for HEOR database analyses; familiarity with R preferred
  • Experience in health economics or outcomes research in oncology biopharma or diagnostics preferred
  • Familiarity with major health economics databases, e.g. MarketScan, MEPS
  • Familiarity with epidemiological databases and modeling, preferred

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.