Research Technician – Infectious Disease Drug Discovery

Location
Saranac Lake, NY
Posted
May 10, 2022
Required Education
Bachelors Degree
Position Type
Full time

Research Technician – Infectious Disease Drug Discovery

The successful candidate will have wet lab experience in microbiology, biochemistry, and/or molecular biology, which they will apply to develop and optimize biochemical assays of drug efficacy, as well as to construct genetically engineered mycobacterial strains with utility in mechanism of action determination and target identification. We seek a detail-oriented team member who enthusiastically engages in shared tasks and has a drive to advance their knowledge, with demonstrated skill in planning, prioritizing, and executing projects to meet commitments. Experience with preclinical animal models and cell culture is desirable.

Responsibilities:

  • Apply microbiology and molecular biology techniques to genetically engineer microbes for target deconvolution and recombinant protein expression.
  • Express and purify recombinant proteins from various bacterial pathogens for in vitro biochemical assays to determine small molecule inhibitor efficacy.
  • Mammalian and bacterial cell culture, and preparation of viral stocks using aseptic culture techniques, transformation, transduction, infection and viability assays.
  • Record and analyze data, as well as write and present reports on research findings.
  • After required training, conduct some studies in a biosafety level 3 (BSL3) environment.
  • Assist in studies of antimicrobial efficacy in mouse models of mycobacterial disease.
  • Preparation of growth media, solutions, and laboratory supplies.
  • Perform other tasks as required

Knowledge and Skill Requirements:

  • Bachelor’s degree (B.S.) in biological sciences or related discipline.
  • Knowledge of recordkeeping practices.
  • Ability to interact with various people using tact and discretion.
  • Work effectively despite interruptions.
  • Ability to work as part of a team and independently utilizing good judgment.
  • Knowledge of written and oral communication skills sufficient to permit clear and effective exchange of information with people representing a wide diversity of discipline and levels of sophistication. 
  • Detail oriented and an ability to organize tasks, reports, or other documentation to maintain regulatory compliance.