Research Associate: Single B-Cell Antibody Discovery

Employer
Abveris
Location
Canton, MA
Posted
May 08, 2022
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time

Overview

Abveris is Boston's premier antibody discovery company providing contract research services to the biopharma industry. Abveris applies advanced immunization methods combined with B cell screening and hybridoma-based antibody discovery technologies to provide comprehensive gene-to-antibody discovery services. Abveris is developing the next generation of biologics, cell therapies, vaccines, and diagnostics in partnership with global leaders in biopharma.

Abveris is a division of Twist Bioscience that prides itself in integrity, teamwork, drive, innovation, and our partner’s successes in biologics development. We provide our hard-working team with a generous vacation policy, a matching retirement plan, and free lunch every day.

 

About

We are seeking a motivated individual to join our team and expand our high-resolution single B-cell screening platform using the Berkeley Lights Beacon. Using state-of-the-art technology coupled with intelligent project and assay design, the candidate would accelerate our antibody discovery process and guide selection of ideal single B cells. Highly qualified candidates will be able to combine exemplary benchwork with the ability to analyze complex data sets and translate them into actionable, intelligible data reports.

 

Responsibilities

  • Application of microfluidics-based selections of antigen-specific B cells using the Berkeley Lights Beacon.

  • Careful preparation and thorough validation of protein reagents and cell lines for single B cell antibody discovery workflows.

  • Execute and troubleshoot antibody-based functional assays (protein-protein interactions and cell-based), particularly on the nanoscale level.

  • Complex instrumentation troubleshooting and maintenance.

  • Effectively communicate and coordinate work within a highly matrixed workflow and collaborative environment.


Preferred Qualifications 

  • Undergraduate degree in biology, chemistry, bioengineering, or a related discipline.

  • At least 2 years of relevant experience in a laboratory setting (strong preference to industry experience).

  • Proficiency in aseptic technique for mammalian cell culture.

  • Strong quantitative, organization, and problem-solving skills.

  • Ideal candidates will have experience establishing and validating antibody-based functional assays and characterization processes.

  • Productive and adaptable in a dynamic setting with multiple projects under specific timelines.

  • Keen understanding of the antibody discovery process a plus.

  • Exceptional verbal and written communication skills.

  • Detail oriented with proven ability to troubleshoot complex problems with diverse variables.