Research Associate: Single B-Cell Antibody Discovery

Overview

Abveris is Boston's premier antibody discovery company providing contract research services to the biopharma industry. Abveris applies advanced immunization methods combined with B cell screening and hybridoma-based antibody discovery technologies to provide comprehensive gene-to-antibody discovery services. Abveris is developing the next generation of biologics, cell therapies, vaccines, and diagnostics in partnership with global leaders in biopharma.

Abveris is a division of Twist Bioscience that prides itself in integrity, teamwork, drive, innovation, and our partner’s successes in biologics development. We provide our hard-working team with a generous vacation policy, a matching retirement plan, and free lunch every day.

About

We are seeking a motivated individual to join our team and expand our high-resolution single B-cell screening platform using the Berkeley Lights Beacon. Using state-of-the-art technology coupled with intelligent project and assay design, the candidate would accelerate our antibody discovery process and guide selection of ideal single B cells. Highly qualified candidates will be able to combine exemplary benchwork with the ability to analyze complex data sets and translate them into actionable, intelligible data reports.

Responsibilities

• Application of microfluidics-based selections of antigen-specific B cells using the Berkeley Lights Beacon.

• Careful preparation and thorough validation of protein reagents and cell lines for single B cell antibody discovery workflows.

• Execute and troubleshoot antibody-based functional assays (protein-protein interactions and cell-based), particularly on the nanoscale level.

• Complex instrumentation troubleshooting and maintenance.

• Effectively communicate and coordinate work within a highly matrixed workflow and collaborative environment.

Preferred Qualifications 

• Undergraduate degree in biology, chemistry, bioengineering, or a related discipline.

• At least 2 years of relevant experience in a laboratory setting (strong preference to industry experience).

• Proficiency in aseptic technique for mammalian cell culture.

• Strong quantitative, organization, and problem-solving skills.

• Ideal candidates will have experience establishing and validating antibody-based functional assays and characterization processes.

• Productive and adaptable in a dynamic setting with multiple projects under specific timelines.

• Keen understanding of the antibody discovery process a plus.

• Exceptional verbal and written communication skills.

• Detail oriented with proven ability to troubleshoot complex problems with diverse variables.