Bioinformatics Scientist

We are currently searching for a Bioinformatics Scientist to provide Bioinformatics related duties support to the Cohorts Data Analytics Core. This opportunity is full-time, and it is on site in Bethesda, MD.  

• Optimize and maintain best practice pipelines to determine Phenotype Risk Score PheRS and perform PheWAS, LabWAS, TWAS, and similar analyses
• Use and maintain large-scale genotype and phenotype databases
• Build computable phenotypes for disease, drug effects, and other conditions using combinations of EHR data and survey data
• Develop scripts that analyze a variety of health-related data and combine data across different orthogonal data sets, such as EHR data, environment, taxonomical knowledge resources such as OMIM, human phenotype ontology, or Drug bank to aid in genomic analyses
• Provide broad-based programming and analytic support for a wide variety of informatic and genomic research projects; write custom scripts to analyze public or data generated in the laboratory
• Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects
• Perform computational analysis of and interpret results
• Provide detailed documentation of custom scripts
• Develop or share tools via simple websites
• Participate in research design with investigators for determining best practices pertaining to the bioinformatics analysis in new and ongoing projects
• Identify new tools and resources for reaching biologically meaningful conclusions.
• Work on multiple projects concurrently with other laboratory members
• Interact with and advise other NIH researchers to translate research phenotype and analysis ideas into requirements for projects to be executed within the cohorts that we maintain access to
• Collaborate with group members in experiments associated with data collection
• Attend group meetings; present findings; author publications resulting from projects

# SOAR

#LI-JR1

• Experience in creating data management tracking systems, data and analysis quality control, error-checking procedures, and back-up procedures to prevent loss of data
• Experience in large-scale analyses in the high-performance computing environment or cloud-based environment
• Ability to quickly convert analysis ideas to implementation, and to multi-task on different projects
• Work with large data sets
• Genome-wide association studies
• Microarray data analysis
• Whole Genome Sequencing
• Whole Exome Sequencing
• Clinical Data Analysis
• Gene-Burden Analysis
• Multi-omics Analysis
• Data Harmonization
• Core facility
• SQL
• R
• Perl
• Java
• Python
• Bash
• Experience with electronic health record (EHR) a plus
• Experience with OMOP or HL-7 a plus
• Experience with All of Us, UK biobank and the eMERGE is a plus
• Ability to use version control systems, such as GitHub is a plus
• Experience in creating data management tracking systems, data and analysis quality control, error-checking procedures, and back-up procedures to prevent loss of data
• Good collaborative work ethics in a group environment
• Jupyter Notebooks

Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) was acquired in October 2021.

Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.

Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco.

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