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Research Associate II or III - Analytical Development (Cell Biology)

Employer
Precision BioSciences, Inc.
Location
Durham, NC
Start date
May 6, 2022

Job Details

Summary

 

The Research Associate II or III will work in the Cell Therapy Bioassay/Immunoassay/Flow Cytometry team of Precision BioSciences. This individual will provide biologic analytical support for Product Sciences and Cell Therapy Process Development projects. The position will contribute to development efforts for CART-cell projects by providing sample preparation and analysis in a timely manner.  This position is lab-based and will share facilities and resources with the Cell Therapy teams.

**Please note, Precision BioSciences mandates COVID-19 vaccination of all employees. Accommodations may be made in accordance with applicable law.

Essential Duties and Responsibilities

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.  This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.

 

Primary responsibilities will include:

  • Design, develop, characterize and document analytical methods for the phenotypic characterization of genome-edited cell therapy products
  • Execute established assays and analyze data according to SOPs and report results of analysis to team leaders in a timely manner
  • Multi-color Flow Cytometry
  • Immunoassay
  • Bioassay
  • Coordinate with team members to plan and conduct experiments that need to be carried out in a timely manner to achieve Precision’s development goals
  • Work collaboratively on aspects of experiments to be performed by other members of the team as part of larger ongoing experiments
  •  

    Qualifications

    The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.

     

    Education/Experience

     

    Required:

    • Bachelor’s degree (B.S/B.A.) in the biological sciences or related discipline and 2+ years of related biopharma industrial experience and/or training, or equivalent combination of education and experience

     

    Preferred:

    • Experience in multi-parametric flow cytometry
    • Experience with cellular immunology assay development, including multiplex cytokine analysis and immunological functional assays
    • Familiarity with immunology and T cell biology
    • Experience with mammalian cell culture
    • Understanding of drug substance and drug product release testing methodologies

     

     

    Travel Requirements

    • Minimal travel is required for this position. Opportunities to participate in conferences, seminars and workshops will be available and encouraged.
     

    Location

    · This is an office-based position located at the main headquarters in downtown Durham, NC.

     

     

    Precision BioSciences’ mission and vision is to translate the world’s most powerful genome editing technology into greatly needed products throughout the life sciences, by being the conduit through which the greatest genome engineering challenges are solved. Precision’s wholly proprietary ARCUS genome editing platform enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome. Through our ARCUS platform, we are developing genome editing-based products to address critical needs in oncology, genetic disease, agriculture, and beyond. For additional information, please visit www.precisionbiosciences.com

     

    Precision BioSciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

     

    Company

    Precision BioSciences, Inc. (Nasdaq: DTIL) is a clinical stage gene editing company developing in vivo gene editing and ex vivo allogeneic CAR T therapies with its highly precise and versatile ARCUS genome editing platform. ARCUS uses sequence-specific DNA-cutting enzymes, or nucleases designed for gene knock out, as well as highly sophisticated edits for gene insertion and/or gene repair. Precision’s in vivo gene editing pipeline consists of wholly-owned preclinical candidates for primary hyperoxaluria type 1 (PBGENE-PH1), familial hypercholesteremia (PBGENE-PCSK9) and chronic hepatitis B (PBGENE-HBV). It has also partnered with Lilly to develop candidates for Duchenne muscular dystrophy and two other programs targeting the liver and CNS. Precision’s allogeneic CAR T pipeline consists of multiple investigational candidates in early-stage clinical trials, including its first and second generation CD19 targeting candidates PBCAR0191 and PBCAR19B for relapsed and/or refractory (R/R) non-Hodgkin and B-cell lymphoma patients. Precision has also prioritized development of PBCAR269A, its BCMA targeted candidate in combination with a gamma secretase inhibitor for R/R patients with multiple myeloma. Precision BioSciences and its in-house manufacturing facility for AAV, mRNA, and CAR T cells is based in Durham, North Carolina. For more information about Precision BioSciences please visit www.precisionbiosciences.com

    Stock Symbol: DTIL

    Stock Exchange: NASDAQ

    Company info
    Website
    Phone
    919-314-5512
    Location
    302 East Pettigrew Street
    Durham
    North Carolina
    27701
    US

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