Research Associate, New Targets

Avidity Biosciences is pioneering a new class of therapeutics called Antibody Oligonucleotide Conjugates (AOC™). We utilize our proprietary AOC platform to design, engineer, and develop therapeutics that combine the tissue selectivity of monoclonal antibodies (mAbs) with the genetic precision of oligonucleotides to access previously undruggable tissues and cell types. We are advancing a pipeline of therapeutic programs focused on rare muscle disorders and other diseases with unmet medical need. We are passionate about the impact of every employee in bringing these potentially transformative therapeutics to patients in need. Make a difference with us.

Avidity is seeking an enthusiastic and dedicated Research Associate to join our Discovery Biology team who can assist with ongoing studies that aim to expand our AOC platform. This is a hands-on research position, and a successful candidate will have a proven record of producing exceptional results in a laboratory setting. 

• Perform experimental assays in support of Avidity’s AOC platform expansion programs
• Execute detailed protocols and techniques necessary for several molecular and cellular biology assays
• Source, maintain, and manipulate mammalian cells in culture
• Adapt protocols and techniques to high-throughput assays in 96- & 384-well plate-based formats
• Collaborate with other members of the Discovery Biology team as well as other teams throughout Avidity to deliver on corporate goals
• Analyze data and interpret results into a professional, presentable format
• Document procedures and results in an electronic lab notebook

• A B.S./B.A. degree in the biological sciences with 1-2 years of relevant wet lab experience, preferably in an industry setting
• Proficient in techniques critical for molecular and cellular biology experiments, including RNA isolation, quantitative PCR, immunohistochemistry, and western blotting
• Proficient with mammalian cell culture, including caring for and passaging immortalized cell lines and siRNA transfections. Experience with isolating and culturing primary cells and maintaining/ differentiating stem cell lines is a plus
• Demonstrated strong skills in aseptic techniques as well as proper handling of chemotherapeutics and protein biologics
• Proficient computer and data analysis skills specifically with Microsoft Office Suite and GraphPad Prism
• Enthusiastic attitude to work independently and in a project team-oriented environment

Physical Requirements/Demands

• Repeating motions that may include the fingers, wrists, hands and/or legs
• Remaining in a stationary position, often standing or sitting for prolonged periods
• Adjusting or moving objects up to 50 pounds.
• Operating machinery and laboratory equipment

Environmental Conditions

• Low temperatures
• Noisy environments
• Exposure to general laboratory environment conditions.
• Exposure to general office environment conditions.