Senior Director, Translational Medicine

We are looking to add a Sr Director, Translational Medicine to our growing team. As an integral member of our science leadership team, this role will be responsible for collaboratively directing and managing our pharmacodynamic and diagnostic biomarker programs and executing Zai Lab’s strategic research and clinical roadmap.

This role offers the opportunity to play a key role in a strong multi-disciplinary scientific team while tackling important and challenging therapeutic targets. Our ideal candidate will have a track-record of excellence taking oncology research concepts and translating them into clinical applications, and will have the aptitude for working in collaboration with our existing drug discovery and development core groups.

• Collaborate with our biology team to plan and prioritize translational medicine workflows across our portfolio, including our existing programs and licensed programs
• Guide the transition of our research programs into pre-clinical development and beyond
• Select and manage external collaborations and contract vendors to ensure successful transition into the clinic
• Help build a high value pipeline as a part of the science leadership team working collaboratively to identify and evaluate new target opportunities, and assessing the full scope of potential therapeutic applications for our existing programs
• Work with management and translational medicine team to ensure success of translating preclinical programs to human disease

• Ph.D in Biology (or M.D. with Oncology training), required. Post-doctoral research in cancer biology, preferred
• 10+ years of industry experience in discovery and translational research for cancer biology
• Experience advancing a small molecule drug from preclinical to a clinical setting
• Possess a broad understanding of cancer targets and respective therapeutic mechanism of action
• Experience working with cross-functional teams in biology, chemistry, pharmacology and DMPK groups
• Experience with the interpretation of ADME data and correlating data to pharmacodynamic effects
• Experience in leading the development of pharmacodynamic markers from basic research, through drug optimization, and translation to clinical setting
• Experience in leading translational strategy to early development, while allowing for the differentiation of programs from competitors
• Able to promptly evaluate and prioritize concepts, maintain internal focus with respect to resources, and manage your time efficiently
• Able to make a fast “no” decision to maintain focus on productive endeavors
• Experience with clinical proof of concept work
• Excellent communication skills, both verbal and written

Zai Lab US requires all employees who are working onsite or who are in customer facing positions to be vaccinated against COVID-19 (subject to any legally required exemptions)

Disclaimer: This description is not intended to be construed as an exhaustive list of duties, responsibilities, or requirement for the position. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or based on disability.