Research Technologist- Histology & Light Microscopy Core

San Francisco, CA
May 03, 2022
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
Lab/Area:Histology Core


We are currently looking to hire a Research Technologist in the Histology & Light Microscopy Core. The person in this position will be reporting to the Histology & Light Microscopy Core Director.

  • Must be able to work within a core laboratory, providing Histology & Microscopy services to researchers both at Gladstone Institutes and beyond.

  • Applies basic technical knowledge of the principles, concepts and methods of biomedical research to perform various analyses and supporting the investigation of scientific problems.

  • Will be joining a team who are responsible for the core request workload where types of experiments vary greatly day by day.

  • Assist in the operation and maintenance of scientific equipment such as tissue processors, microtomes, slide stainers, cryostats and microscopes.

  • Perform research techniques and procedures such as tissue grossing, processing, embedding, cutting, routine and special staining plus slide mounting and quality control.

  • Assist in the development of new core procedures and experimental protocols for researchers.

  • Perform, or receive training in Immunohistochemistry.

  • Perform, or receive training on, bright field, polarizing, epifluorescence, confocal and light sheet microscopy.

  • Perform automated image analysis using tools such as ImageJ and Imaris.

  • Ensure lab cleanliness and safety.

  • Maintain stocks and reorder as necessary.

  • Responsible for updating core inventories and electronic records, responding to user queries, scheduling and performing user equipment training and consulting with users on experimental design

Skills required:

  • Histology skills are a must; tissue fixation, paraffin and cryo-section cutting plus routine and special staining.

  • Light microscopy experience is preferred.

  • Able to communicate verbally in a clear and concise manner with a varied group of researchers from many different background and histological experience

  • Demonstrates understanding of directions by providing regular feedback on work activities

  • Asks questions to gather additional information.

  • Resolves routine and recurring problems within own work area

  • Highly organized (punctual, respectful for other lab members and users time, ability to answer emails with quick turn around).

  • Approachable and helpful; accountable for workload and duties

  • High work ethic and a genuine passion for scientific inquiry

Required qualifications:

  • Associates degree and 2+ years of relevant experienc

  • BA/BS in a biological, chemical or physical science

  • MS in a biological, chemical or physical science

  • Expertise should include working knowledge of and technical experience with research (animal) histology techniques.

  • Ability to interact with researchers on a scientific and functional level.

  • Light microscopy and digital and image analysis experience is a plus.

  • Good computer skills, including proficiency with Microsoft Word, Excel, and PowerPoint.

  • Basic familiarity with R, Python or other programming language is desirable but not required.

  • Basic anatomical knowledge and experience with animal dissection is desirable but not required.

  • Immunohistochemistry experience and in-situ hybridization experience is a plus.

Additional Information:
  • Title and salary will be commensurate with education and experience.
  • Gladstone is an equal opportunity employer.