Research Associate, Genomics

South San Francisco, CA
May 02, 2022
Required Education
Bachelors Degree
Position Type
Full time

Graphite Bio is a clinical-stage, next-generation gene editing company harnessing high efficiency targeted gene integration to develop a new class of therapies to potentially cure a wide range of serious and life-threatening diseases. Graphite Bio is pioneering a precision gene editing approach that could enable a variety of applications to transform human health through its potential to achieve one of medicine’s most elusive goals: to precisely “find & replace” any gene in the genome. Graphite Bio’s platform allows it to precisely correct mutations, replace entire disease-causing genes with normal genes or insert new genes into predetermined, safe locations. The company was co-founded by academic pioneers in the fields of gene editing and gene therapy, including Maria Grazia Roncarolo, M.D., and Matthew Porteus, M.D., Ph.D.

Learn more about Graphite Bio by visiting and following the company on LinkedIn.

The Role:

We are seeking a talented Research Associate/ Senior Research Associate to join our Genomics team. In this role you would leverage a range of next generation sequencing assays to drive biological research and development activities and to support our translational pipeline based on gene correction in hematopoietic stem cells.

What You Will Do:

    • Conduct next generation sequencing experiments to characterize gene editing outcomes
    • Run single cell sequencing experiments to analyze edited cells and patient samples
    • Utilize NGS assays to shape the development of next generation gene editing approaches
    • Run and maintain various genomics and liquid handling instruments
    • Support drug product release and characterization by aiding the development of fit-for-purpose methods
    • Generate data and ensure high-quality documentation for regulatory submissions and publications

What You Will Bring:

    • Bachelor’s or Master’s degree in biology, genetics, molecular biology, cell biology, or equivalent
    • 2+ years of hands-on work in a laboratory setting required; prior experience in biotech preferred
    • Strong background in molecular biology (different PCR techniques, enzymatic DNA or RNA processing, nucleic acid purification and QC, CRISPR gene editing)
    • Familiarity with lab instrumentation, including plate readers and liquid handlers
    • Experience with standard DNA and RNA NGS workflows highly desired
    • Impeccable attention to detail and meticulous documentation of experiments and results
    • Excellent communication, organization, interpersonal, and scientific writing skills
    • Ability to positively impact company culture and demonstrate flexibility in a fast-paced environment

What Graphite Will Bring:

At Graphite Bio, we are intentionally building a community that is inspired, diverse, and curious. For this role, and all roles, we seek someone who is:

  • Determined. You share our mission to bring curative gene editing to patients. And you know the need is urgent.
  • People-focused. You prioritize relationships. You value differences and are an excellent listener.
  • Adaptable. You seek solutions, even when things change. You prefer to find your way to “yes!”

EEO Statement

Graphite Bio is an equal opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end. 

COVID-19 Policy

All company employees, regardless of work location, must be fully vaccinated for COVID-19. Fully vaccinated means a person has received all recommended doses in their primary series COVID-19 vaccine. Requests for an accommodation/exemption for medical or religious reasons, as well as under applicable state law, will be considered on a case-by-case basis consistent with applicable law.

  To all recruitment agencies: Graphite Bio does not accept agency resumes or applications. Please do not forward resumes to our jobs alias, or Graphite Bio employees. Graphite Bio is not responsible for any fees related to unsolicited resumes or applications.