Scientist III, NMR Laboratory

Rockville, MD
May 01, 2022
Required Education
Position Type
Full time

Summary of the Position

This is a hands-on technical position, in USP’s Nuclear Magnetic Resonance Laboratory, in the Global Laboratory and Technical Operation Division. In this role, the Scientist III delivers sustained contributions that result in innovative product and process technologies for USP. The Scientist III will contribute to the scientific expertise and work ethic of the laboratory through a broad range of technical knowledge. The Scientist III will be an integral member of the Nuclear Magnetic Resonance spectroscopy (NMR) team and will assist in the execution of structural elucidation of chemically diverse organic compounds by NMR methods. A Scientist III has mastered many common NMR techniques with the laboratory and is able to contribute their own observations and input to difficult projects. The Scientist III may execute 90% - 100% of their work at the bench level.

Roles and Responsibilities

• Works independently to develop testing methodologies for the analysis of drug substances, drug products, dietary substances, and excipients. 

• Demonstrates solid scientific approach to analysis in the laboratory. 

• Provides hands-on NMR sample preparation, multinuclear as well as multidimensional NMR data acquisition and processing. Focuses on assessing data interpretation and analyzing the structures of small to large molecules in support of the USP catalogue. 

• Helps to strengthen an in-house NMR lab consisting of 600 MHz, 500 MHz, and 400 MHz spectrometers equipped with cryoprobes and automation.

• Collaborates with other Scientists in Laboratory, by providing support for the reference standards program by ensuring the successful completion of departmental projects on time with the highest quality.

• Evaluates current and proposed USP reference standards using NMR methods including the preparation of detailed, professional reports prepared internally.

• Provides NMR analysis, specifically structure elucidation, verification, and confirmation services to internal customers.

• Use additional software’s such as ACD, Mnova, and CRAFT towards Reference standards analyses.

• Demonstrates strong skill and expertise in specific laboratory methods.

• Recommends improvements to NMR methods and laboratory processes.

• Seeks out innovative ways to apply knowledge or skills to improve protocols and results.

• Actively engages overall project and ensures own work in aligned with overarching goals.

• Takes personal ownership of work assigned.

• Records experimental data, ensuring clear and accurate transcription of results and calculations.

• Routinely applies personal experience, academic training, and technical insights to solve complex problems in the laboratory.

• Participate towards authoring scientific manuscripts. 

• Demonstrates a strong desire to continue learning and grow personal capability.

Basic Qualifications

Ph.D. in Natural Products chemistries with graduate research and postdoctoral experience focused on natural products structural elucidations, stereochemical and conformational analysis, primarily using NMR spectroscopy, and other complementary techniques.

Preferred Qualifications

• 0-4 years postdoctoral experience 

• Experience working in the pharmaceutical/ dietary supplements/nutraceutical industries. Working knowledge of methods and procedures, and expertise in calibrating and operating NMR equipment required. 

• Must have demonstrated success in utilizing NMR techniques for stereochemical analyses. 

• Experience working with natural products by modern methods of NMR including data collection, as well as data interpretation as applied to structural elucidation. Good understanding of conformational changes and stereochemical assessment.

• Exposure to quantitative NMR techniques is a plus. 

• Ability to maneuver and handle projects between two instrumental platforms (BRUKER & JEOL) is essential. Takes personal responsibility to ensure work is delivered on time and is the highest possible quality. 

• Skill to anticipate, troubleshoot and solve technical problems.

• Experience in development, execution and/or validation of complex analytical procedures.

Supervisory Responsibilities

This is a hands-on laboratory position with no supervisory responsibilities.


USP provides you with the benefits you need to protect yourself and your family today and tomorrow. From company-paid time off, comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial wellbeing are protected.

About USP

The U.S. Pharmacopeial Convention (USP) USP is an independent scientific organization that collaborates with the world's top experts in health and science to develop quality standards for medicines, dietary supplements, and food ingredients. USP brings together more than 1,100 talented professionals across five global locations to deliver its mission to strengthen the supply of safe quality medicines and supplements worldwide. USP is proud to be an equal employment opportunity employer (EEOE) and affirmative action employer. Employment selection and related decisions are made without regard to sex, race, age, disability, religion, national origin, color, veteran status, sexual orientation, gender identity or any other protected class. We are committed to working with and providing reasonable accommodation to individuals with disabilities. USP does not accept unsolicited resumes from 3rd party recruitment agencies and is not responsible for fees from recruiters or other agencies except under specific written agreement with USP. 


The following COVID-19 provisions will apply to selected candidate(s) hired: 


As a condition of employment with United States Pharmacopeial Convention’s (USP) duty to provide and maintain a workplace that is free of known hazards, all employees and contingent staff hired after July 1st, 2021 are required to be fully vaccinated unless a reasonable accommodation is approved. Your recruiter will advise accordingly.