Scientist, Analytical Chemistry

Regeneron Pharmaceutical’s Analytical Chemistry Group is seeking an innovative and team oriented Scientist to join our group. In this role, you will work with LC-MS technologies to guide and support development and characterization of therapeutic protein drug candidates. You will apply expertise and solid understanding of various LC-MS platforms and applications to tackle analytical problems. The ideal candidate will have a robust background in mass spectrometry-based protein analysis, strong critical thinking skills, a passion for science, and effective interpersonal and communication skills to work efficiently in cross-functional teams and achieve program goals.

A TYPICAL DAY IN THE ROLE OF A SCIENTIST MIGHT LOOK LIKE:

• Design, execute, and optimally communicate analytical characterization of biotherapeutics, including monoclonal and bispecific antibodies, Fc-fusion proteins, and other modalities (adeno-associated virus, siRNA, etc.) to support drug development.
• Lead and deliver on characterization activities to elucidate product quality attributes like post-translational modifications, sequence variants, charge variants, size variants, and host cell proteins.
• Form and maintain inter-departmental collaborations to solve any potential drug development issues.
• Proactively find opportunities to advance LC-MS analysis of biotherapeutics by developing technical innovations that will contribute to future developmental needs and/or efficiency gains.
• Document experiments, results, and findings in electronic laboratory notebook (ELN) entries.
• Present results during internal and external meetings
• Prepare and review regulatory submission documents like IND, comparability, and BLA reports, as well as manuscripts for publication in peer-reviewed journals.
• Serve as a team representative and provide analytical knowledge and expertise to cross-functional teams.

• You are a critical-thinker and excel at identifying and solving problems.
• You thrive in creative and flexible team environments.
• You are highly-motivated and can lead and coordinate projects in a timely manner.

This role requires a PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field, with 0-4 years of proven experience and a record of publications involving mass spectrometry-based analysis of proteins. Extensive experience with mass spectrometers (Q-TOF, Orbitrap, Q-Exactive, Triple Quadrupole, etc.), liquid chromatographs, and data processing software (Proteome Discoverer, Skyline, Protein Metrics, MaxQuant, etc.) is desired. You must be detailed, diligent, highly efficient, and capable of collaborating within a team and with external partners. Excellent written and verbal communication skills are also crucial to this position.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.