Scientist - Therapeutics
- Employer
- BioSpace Recruitment Services
- Location
- 94080, South San Francisco
- Start date
- Apr 26, 2022
View more
- Discipline
- Science/R&D, Bio-Assay Development, Biotechnology, Biotherapeutics, Cell Biology, Chemistry, Laboratory, Molecular Biology, Pharmacology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
You need to sign in or create an account to save a job.
Key Responsibilities:
- Design and execute in vitro experiments, analyze and interpret data to support discovery and preclinical development using a variety of readouts
- Work with a diverse and cross-functional team of wet-lab scientists and external collaborators to generate key datasets that are critical for the declaration of development candidates
- Develop and validate PD biomarkers that can be applied both preclinically and clinically
- Build and conduct validation assays to demonstrate proof-of-concept of a new platform in therapeutically relevant areas
- Maintain accurate and complete documentation of experimental results for study reports and regulatory submissions
Qualifications:
- Ph.D. in RNA biology, neurobiology, or oligonucleotide chemistry (or a relevant scientific discipline) with 2+ years experience in biotechnology and/or drug development
- Experience in bioinformatics for genomics, NGS, and a programming language (R, Python) is preferred
- Extensive knowledge of and experience with pharmacology, PK-PD relationships, and interrogating molecular target engagement and downstream physiological endpoints
- Familiarity with cellular assays (e.g., cell lines, primary cells, neurons, IPSCs)
- Hands-on experience with molecular biology including qPCR, western blots, and plate-based immunoassays (e.g., ELISAs, MSD, Luminex)
- Creativity and the ability to work and debate constructively within an interdisciplinary team to achieve technical success and corporate milestones
- Strong experience in statistical analysis software (e.g., Graphpad Prism)
- Familiarity with data capture, analysis, and visualization within an Electronic Lab Notebook
- Results-oriented individual with exceptional organization, attention to detail, scientific versatility, flexibility, critical thinking, and communication skills
- Experience in a managerial role is preferred
You need to sign in or create an account to save a job.
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert