Senior Research Associate/ Associate Scientist/ Scientist, CMC

Location
92121, San Diego
Posted
Apr 26, 2022
Hotbed
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time

Ansun Biopharma is a clinical stage biotechnology company with several programs in the pipeline including oncolytic virus, CAR NK cell therapy and Phase 3 biologic targeting PIV. Ansun is seeking a highly motivated, organized, and energetic individual to join the CMC team. The successful candidate will have relevant experience within a CMC setting preferably with a focus on methods development.

Ansun Biopharma has an opening for a Senior Research Associate/Associate Scientist/Scientist within the CMC team with the title reflecting the candidate’s experience. The candidate will work within the MC department to support programs within the company including CAR NK cell therapy and oncolytic virus methods development. The candidate should have relevant research experience in method development and validation, molecular biology, immunology, and/or virology. The candidate will assist senior members of the CMC team with development of analytical methods, characterization of processes, and perform general laboratory maintenance tasks. The successful candidate will be an effective team player, flexible, able to follow protocols, multiple tasks, and deliver high quality results under tight timelines.

Responsibilities

  • Support senior members of the CMC department with developing rugged and reliable bioassays utilizing various molecular biology methods such as qPCR, flow cytometry, in-cell western blotting, ELISAs, and various cell or non-cell based assays.
  • Perform in vitro studies to evaluate and optimize the effectiveness of bioassays.
  • Support scale up of cell expansion and process monitoring, support cell line development, analyze end of process products using validated methods such as multi-color flow cytometry
  • Follow detailed protocols, maintain appropriate documentation, and keep detailed records in electronic laboratory notebook.
  • Follow SOPs to maintain CMC utilized equipment
  • Present experimental results to cross-functional teams with the CMC department and externally.
  • Perform other duties and tasks as assigned.

Qualifications

  • BSc with 5 years of experience, MSc with 3 years of experience, or PhD with 1 year of relevant industry experience with a background in Molecular Biology, Immunology, Virology or a related discipline.
  • Comprehensive experience in aseptic cell culture techniques of mammalian cells are required.
  • Outstanding organization skills is required.
  • Clear and consistent verbal and written communication skills using are required.
  • Experience in an analytical role within a CMC department is highly desired
  • Experience with NK or Oncolytic virus based assays such as cytotoxicity, multi-flow cytometry, reporter based assays is highly desired
  • Strong background in molecular biology techniques is desired such as molecular cloning, PCR/qPCR, cell based assays, cell culture expansion, and cell banking.
  • Proactive, hard-working, and a desire to learn a variety of new skills

Preferred Qualifications

  • Previous CMC experience in assay development with 2+ years of industry experience.
  • Previous GLP/GMP experience is a plus.
  • Experience with 8+ color flow cytometry
  • Experience with in vitro cell-based reporter assay development.

Benefits

  • Employee Incentive Stock Options
  • Medical, Dental, & Vision Coverage
  • Paid Vacation & Sick Time
  • Life & Disability Insurances
  • 401(k) Retirement plan
  • Flexible Spending Account (FSA)

Ansun Biopharma is an Equal Employment Opportunity/Affirmative Action Employer: Minority/Female/Disability/Veterans/Sexual Orientation and Gender Identity.

We are committed to providing reasonable accommodations, if you need an accommodation to complete the application process, please contact HR; 858-452-2631.

https://www.ansunbiopharma.com/