Associate Director, In Vivo Pharmacology

Zai Lab (NSDAQ: ZLAB) is an innovative, research-based, commercial stage biopharmaceutical company based in China and the U.S. focused on bringing transformative medicines for cancer, autoimmune and infectious diseases to patients in China and around the world.

Headquartered in Shanghai since our founding in 2014, our experienced team has secured partnerships with leading global biopharma companies, generating a broad and late-stage pipeline of innovative drug candidates. Based on our extensive track record of execution and delivering results, Zai Lab has earned the reputation as a trusted partner of choice for global biopharmaceutical companies seeking to not only access the Chinese market but also find a long-term strategic partner for global clinical development.  Through these partnerships, Zai Lab has built the strongest late stage oncology portfolio with global first-in-class and/or best-in-class profile, among innovative Chinese biotech companies. We are further supplementing our pipeline with an in-house discovery effort aiming to produce 1-2 global INDs per year.

Zai Lab is rapidly expanding into a fully integrated biopharmaceutical company, discovering, developing, manufacturing and commercializing innovative medicines. To that end, we have built our internal R&D center to advance our discovery pipeline, a strong clinical development and operations team, and our own manufacturing facilities in China. We have also established a highly specialized commercial team to support marketing of our innovative products in China. We believe this integrated approach will provide sustainable competitive advantages for Zai Lab.

Zai Lab was successfully listed on the Nasdaq Stock Market in September 2017 and completed secondary listing on Hong Kong Stock Exchange in September 2020. Zai Lab significantly expanded with several offices across China and U.S. and opened its U.S. headquarters in San Francisco in December 2018. As of June 2021, the Company has a global team of over 1600 employees.

Primary Function:

The Associate Director on the Vivo Pharmacology team will focus on executing non-clinical rodent studies to support the identification, validation, and advancement of novel cancer therapeutic candidates. The Associate Director will lead an existing team based at our site in Menlo Park that utilizes rodent models of oncology to support preclinical drug development.

Major Responsibilities and Duties:

• Manage and direct the activities of an existing group of Scientists and Research Associates in the In Vivo Pharmacology department.
• Support in vivo study design and execution across multiple projects to support development of novel anticancer therapeutics. Work to be coordinated will be a combination of internally- and externally-run studies, requiring the ability to identify and work with CRO’s.
• Develop processes for the Pharmacology team, especially for study initiation and completion and data management.
• Analyze and present data, including rationale and design of in vivo studies to the department and project teams, as well as Research Leadership.
• Coordinate the development and implementation of new technologies in the in vivo space to support new target identification, validation, and preclinical development.
• Support the generation of an annual budget for in vivo studies across multiple projects.

• At least 10 years of relevant post-PhD experience. Previous industry experience is required.
• Expert in designing and executing in vivo studies using rodents to support the preclinical development of anticancer therapeutics. Hands-on expertise working with rodent models of oncology is required.
• Excellent management and training skills.
• Experience working with CRO’s to design and execute In Vivo Pharmacology studies.
• Capable of working independently in a fast-paced, team-oriented environment, demonstrating the capability to contribute on multiple projects at the same time.
• Great communication skills and team spirit is required.
• Proven track record of innovation, scientific excellence, and integrity.
• Flexibility to accommodate to rapidly changing priorities and deadlines.
• Excellent troubleshooting and data analysis skills are required.

Diversity Statement:  At Zai Lab we believe a diverse workforce drives our success as a company. We are always working to create an environment where different backgrounds and viewpoints are valued and celebrated.

Zai Lab is an equal opportunity employer. Zai Lab makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.

Recruiter Statement: Zai Lab acknowledges that providers may be a valuable resource for identifying and recruiting candidates for employment.  However, we require that all recruiters engage directly with Zai Lab’s Human Resources Team and comply with Zai Lab’s requirements prior to transmitting any resumes/CVs or introducing any candidates to Zai Lab.  Zai Lab’s Human Resource Team is the only function within the Company that can enter contractual relationships with external recruiters and recruiting agencies.