Sr. Research Scientist I - Biomarker

Sr. Research Scientist I - Biomarker
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

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Job Description:

The Biomarker Sciences department is seeking an experienced scientist who will work in a multidisciplinary team environment to generate and interpret data from translational and clinical studies. The Senior Research Scientist I will be responsible for the development and execution of biomarker strategies for programs in the field of fibrosis and/or inflammation. Experience in the analysis of multi-dimensional data sets and a strong understanding of mechanisms and pathways underlying fibrotic and/or inflammatory diseases is highly desirable.

Responsibilities:

• This position will report to the Director of Biomarker Science in the Fibrosis/Inflammation group
• Lead cross-functional biomarker teams in the execution of clinical biomarker and translational strategies
• Lead the development, validation, and outsourcing of biomarker assays including pharmacodynamic, predictive, prognostic, safety, and other biomarkers
• Collaborate with Research Biology, Clinical Research, and Clinical Data Sciences to generate, analyze, and interpret data from clinical trials and human translational studies
• Strong experimental background in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments
• Experience with genomic, epigenetic, gene expression, metabolomic, multiplexed protein detection or other related emerging platforms or data sets is desirable
• Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environment
• Excellent collaboration, communication, and interpersonal skills are required
• Must be motivated, team and detail-orientated, and results focused

Technical Skills:

• Demonstrated expertise in fibrosis, inflammation, or related field
• Analysis and interpretation of preclinical and clinical biomarker data
• Ability to integrate complex scientific ideas, generate and execute testable hypotheses
• Broad understanding of drug discovery and development in both early and late stage development and familiarity with regulatory approval process
• Knowledge of biomarker discovery and development, including assay development and validation, clinical discovery of biomarkers, and mechanism-of-action/translational studies
• Authoring of biomarker strategy documents and biomarker specific portions of clinical protocols
• Strong verbal and written communication skills
• Proven publication record
• Basic understanding of intellectual property, contracting terms, and provisions

Experience:

• PhD and a minimum of 4+ years of directly relevant post graduate academic and/or industry experience in fibrosis, inflammation, biomarkers, or other related medical science field. Position title will be dependent on related experience.
• Candidate must be detail-orientated with excellent record keeping and organizational skills
• Must be a highly flexible, results-oriented, and independent self-starter who enjoys working in a fast-paced and dynamic multidisciplinary environment.

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