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Research Associate I, Gene Editing Technology (Multiple Openings)

Employer
Mammoth Biosciences
Location
Brisbane, CA
Start date
Jan 21, 2022

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Discipline
Clinical, Medical Writing, Science/R&D, Genetics
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

OPPORTUNITY
Mammoth is currently seeking a talented and detail-oriented Research Associate I with experience in molecular biology, flow cytometry, and/or mammalian cell culture to join our growing genome editing team. The successful candidate will work closely and collaboratively with colleagues to design/develop, perform and execute experiments on mammalian cell lines to support pipeline projects to develop Cas nucleases for genome editing and other applications. They will have the opportunity to contribute broadly across multiple technical areas. The position requires adaptability, excellent planning, strong organizational and communication skills, as well as the ability to work independently in a fast-paced team-oriented, and dynamic environment.

KEY RESPONSIBILITIES
  • Execution of molecular biology, cloning, cell culture, and a broad range of functional assays.
  • Provide team support for basic laboratory tasks including tissue culture of various cell lines, phenotyping and analytical characterization of cells, genome editing of human cells, and virus production
  • Accurately and timely record, document, analyze and communicate laboratory data to senior staff and team members
  • Conducts all activities in a safe and efficient manner, and adheres to site environmental health and safety (EHS) requirements

REQUIRED QUALIFICATIONS
  • Bachelor’s degree in molecular and cell biology, immunology, biochemistry, or a related field

PREFERRED QUALIFICATIONS
  • 3 years of relevant laboratory research experience
  • Extensive experience in molecular cloning
  • Familiarity with gene editing and/or CRISPR/Cas9 
  • Proficiency in mammalian cell culture, PCR, qPCR, genomic DNA and mRNA purification, NGS sequencing, ELISA, western blot, retroviral/lentiviral/AAV transduction
  • Strong organizational and record-keeping skills, excellent interpersonal, verbal, and written communication skills.  Highly motivated with a strong work ethic. Ability to work efficiently and productively in a fast-paced highly collaborative team environment
  • Knowledge of Microsoft Office Suite and other relevant data analysis software (Flowjo, GraphPad Prism, etc.)
  • Industry work experience

BENEFITS
  • Company-paid health/vision/dental benefits
  • Unlimited vacation and generous sick time
  • Company-sponsored meals and snacks
  • Wellness, caregiver, and ergonomics benefits
  • 401(k) with company matching

Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber.

TEAM
Our small-size proteins, such as Cas14 and CasPhi, are poised to transform disease treatment enabling novel editing approaches and delivery options that are difficult to achieve or not even possible with previously described CRISPR-Cas systems. Our teams are responsible for discovering and engineering novel CRISPR systems, and translating our unique CRISPR technology into therapeutic treatments with the ultimate goal of cures for indications with high unmet medical needs.

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law.  This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Company

Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.

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Company info
Website
Phone
(650) 294-8583
Location
South San Francisco
CA
94080
United States

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