Associate, Plasmid and Viral Vector Core

Location
Morrisville, NC
Posted
Jan 21, 2022
Ref
1020
Hotbed
Bio NC
Required Education
Bachelors Degree
Position Type
Full time

Company Summary:

Kriya is a next generation gene therapy company focused on expanding the field to new frontiers. We have built a fully integrated, technology enabled platform for rational vector design, analytical characterization, and scalable manufacturing to design and develop gene therapies for diseases with well-understood underlying biology. We believe that rationally engineered gene therapies can transform the treatment of a broad universe of diseases – and we are prepared to lead this revolution in medicine.

Our team is made up of leading scientific experts who are passionate about improving patients’ lives and easing the burden of these life-changing disorders for patients. We are looking for teammates with the ambition, creativity, and energy to help us build a unique organization.

If you are looking to be a part of a company with an entrepreneurial culture, a bold vision, and a meaningful purpose, Kriya is the company for you.

Position Summary:

We are seeking highly motivated individuals to join the Manufacturing team at Kriya Therapeutics.  The Associate will be responsible for amplification of DNA plasmids and/or production of AAV Vector in our Research Core. 

Primary Responsibilities:

  • Plan and execute production of AAV Vectors utilizing mammalian cell culture in shake flasks and bench scale purification
  • Plan and execute plasmid DNA amplification through bacterial culturing and purification
  • Support lab operations, including inventory management, solution preparation, and standard lab tasks
  • Maintain accurate records and thoroughly document work through data entry into electronic laboratory notebooks, with minimal supervision
  • Prepare, organize, and track sample inventory during production and storage
  • Perform additional lab tasks as assigned

Required Qualifications:

  • Bachelor’s degree preferably in Science, Engineering or other related field and 0-3 years of hands-on lab experience in an academic or industry setting OR
  • Associate degree preferably in Science, Engineering or other related field and 2+ years of hands-on lab experience in an academic or industry setting.
  • Knowledge and hands-on experience utilizing proper lab technique while working with biologics (ex. bacterial or mammalian cultures, proteins, plasmid DNA, viral vectors)
  • Highly self-motivated, organized, and detail-oriented, with proven ability to foster strong relationships with other team members and stakeholders
  • Must have flexible work hours, and be willing to work outside of normal, scheduled hours; as necessary. Must be able to work alternative shift hours and weekends as required
  • Experience with amplification of plasmid DNA and/or production of AAV is preferred 

 

Kriya is an equal opportunity employer. 

We celebrate diversity and are committed to creating an inclusive environment for all employees.