At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science.In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) focuses on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapies. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.
We seek a creative Associate Scientist in the field of Immune-Oncology to join our Lymphoid biology team within the Tumor Microenvironment Thematic Research Center at Bristol Myers Squibb in Redwood City, California. The successful candidate will play an essential role in the discovery of novel therapeutics for the treatment of cancer.
This individual contributor role will collaborate across groups to plan, execute and analyze preclinical discovery studies.A wide range of ex-vivo and in-vitro model systems including human tumor assay systems, MLRs, cell culture, PBMC based isolations and cultures will be used. The qualified candidate is a highly motivated, interactive, and team-oriented individual that possesses the ability to work in a multi-functional team environment. You will gain and provide technical and scientific expertise to advance a variety of drug discovery programs from targetidentification/validation,to IND enabling activities and ultimately to clinical Proof of Concept in patients.
Ideal candidates will havestrong technical skills,immunology background in characterizing the tumor microenvironment and possess excellent communication skills with a strong commitment to scientific objectivity and excellence.We value both what you do and how you do it.
Developing and executing in vitro functional assays to assess killing/activation in the context of drug discovery
Immune profiling of cultured immune cells and tumor infiltrating leukocytes using multi- parameter flow cytometry
Designing and executing ex-vivo functional assay using primary cells of human origin (E.g., blood, tumor)
Analyzing and presenting scientific results to team meetings
Working in a collaborative team environment
Qualifications and Requirements:
BS (3+) or MS (0-2 years) in biology, immunology or a related discipline.
Industry and/or academic experience is desired.
Experience in multi- color flow cytometry is essential
Expertise in immune cell isolation from human peripheral blood
Expertise in in vitro functional assays to assess killing/activation in the context of drug discovery
Experience in ex-vivo functional assay development using primary cells of human origin is desired
Working knowledge in cytokine assessment from culture supernatants using MSD/ ELISA is optional
Experience with data capturing and analysis software (i.e. Flowjo, PRISM, Excel).
Excellent interpersonal and communication skills to interact effectively with internal and external colleagues fostering a collaborative workplace environment.
Detail-oriented, with excellent organizational, and record-keeping skills.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
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