Senior Associate Scientist

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science.In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Summary

We are seeking a highly skilled and enthusiastic protein biochemist/engineer to join the Protein Engineering group as a Senior Associate Scientist. The Protein Engineering group develop and optimize novel antibody-based biotherapeutics to drive specific responses in disease states, in close collaboration with other Discovery Biotherapeutics and Tumor Microenvironment Thematic Research Center (TME TRC) scientists. The candidate will contribute to the protein engineering projects to design, characterize, and optimize novel protein-based therapeutic candidates to modulate immune responses against cancer. The qualified candidate is a highly motivated, interactive, and creative individual who possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary project teams.

Responsibilities

• Support protein engineering efforts to generate and optimize designs for the discovery of novel antibody-based biotherapeutics.
• Design constructs, purify proteins, and assess their design and function through functional assays.
• Develop and implement in vitro cell-based assays to support the discovery of large molecule drug targets.
• Present scientific results and program updates to project teams.
• Accomplish goals under project team timelines.

Requirements

• B.S. in biological sciences with 5+ years or M.S. with 2-5 years of relevant academic or industry experience.
• Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.
• Hands-on experience in protein expression and purification on AKTA instruments is required.
• Hands-on experience with cell culture techniques including isolation and culture of immortalized, primary human and mouse cell lines is required.
• Hands-on experience with multi-color flow cytometry is required and cell sorting is preferred.
• Hands-on experience with a wide range of in vitro biochemical and cellular assays, including Western blotting, ELISA, cellular reporter assay is preferred.
• Hands-on experience with analyzing antibody sequence and structure is a plus.
• Proficiency in utilizing software such as GraphPad Prism, FlowJo, Microsoft Office etc. for data analysis and figure generation is required.
• Basic understanding of any disease biology is a plus.
• Excellent interpersonal skills with the ability to collaborate and interact effectively with colleagues is essential.
• Attention to detail with excellent organizational and record keeping skills is required.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.