Senior Scientist / Scientist Technical Operations - North Carolina

Raleigh, North Carolina
Jan 16, 2022
Required Education
Bachelors Degree
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

GRAIL is seeking a Scientist in Technical Operations in our North Carolina facility. The ideal candidate is a great teammate with hands-on laboratory experience and a willingness to teach others. The candidate will be encouraged to think outside of the box and creatively solve problems while executing NGS-based workflows. They will work collaboratively across many functions of the organization and execute experiments both individually and as a team. The candidate will be instrumental in implementing process improvements, writing documentation, and carrying out day-to-day operations within GRAIL laboratories.
You will:
  • Independently design and conduct experiments to support several automated NGS-based assays
  • Lead or contribute to investigation teams in troubleshooting and root cause analysis across operational functions and workflows
  • Contribute expertise and knowledge to process/product improvement and optimization projects
  • Plan and record studies and investigations performed and recorded in line with regulatory requirements (CAP/CLIA/FDA)
  • Act and present as the Technical Operations SME for materials, specifications, and processes related to current production and development assays

Your Qualifications and Background will include:
  • Minimum of B.Sc./M.S. in Molecular Biology, Biochemistry, or a related field with 5+ years of related experience. Job Title/Level will be based on education and experience
  • Supervisory/mentoring experience and working in project teams
  • Effective written and verbal communication skills (proficiency in English) as well as strong interpersonal, negotiation, and influencing skills
  • Technical leadership, self-direction, and willingness to both teach others and learn new techniques is highly desirable
  • Solid understanding and expertise in clinical diagnostics, medical devices, or equivalent
  • Experience working in a regulated environment under CAP/CLIA and/or FDA, including documentation, change management/control, and non-conformance programs
  • Good planning, prioritization, problem-solving, and organizational skills
  • 2+ years of experience in Next Generation Sequencing assays and workflows preferred
  • Experience with Automated sample preparation or NGS workflows is a plus
  • Experience troubleshooting NGS materials or processes including extraction, library preparation, and enrichment through sequencing is a plus
  • General digital literacy and proficiency in GSuite
  • Data analysis using tools such as JMP, or proficiency with R or Python is a plus

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.