Summer 2022 – Protein Purification Process Development Intern

Intern Supervisor: Scientist II, Purification Process Development
Department: Gene Therapy Process Development
Location: Brisbane, CA

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and proprietary zinc finger genome engineering technology, Sangamo is working to create genomic cures for patients suffering from severe genetic diseases for which today’s medicines can only treat symptoms. At Sangamo, we are committed to creating an inclusive environment that promotes and values diversity. We are dedicated to providing an innovative space where students can engage in meaningful work and collaborate with professionals in the biotech industry through our internship program. Sangamo’s internship program gives students the opportunity to flourish, grow and develop their expertise. We are a company that inspires and empowers everyone who works here to grow and be better than they believe they can be in our mission to collectively transform patients’ lives.

We are seeking passionate, curious, and innovative interns to contribute to our mission. Let’s build a better future together.


What Will You Get Out of This Summer Internship?

• Opportunity to obtain valuable real-world experience in a biotech setting, while gaining specific field-related exposure and making important professional connections.
• Discover if a particular career path or field of study in the biotech industry is right for you.
• Engage in our fun and collaborative company culture while participating in team wide social events.
• Receive compensation through this paid internship.
• Consideration for future full-time positions or contract roles.

Scope of Timeline

• December: Applications open
• Mid- February: Application close (may still consider application if we have openings left)
• February through March: Offers made
• June through August: Internship period

Program Requirements

• Must be 18 years of age prior to scheduled start date
• Must be legally authorized to work in the U.S.
• Must be able to commit to the full 10-12 weeks’ time frame between June and August.
• Interns will be expected to work 40 hours a week.
• Candidates are eligible to apply to the internship within one year of their last degree attained.
• We do not have a GPA requirement.
• Applicants must have completed at least one year of accredited university or community college course work to be considered for an internship.
• We currently do not offer visa sponsorship to interns.

INTERNSHIP PROJECT SUMMARY:  
Sangamo Therapeutics is seeking a highly motivated junior or senior undergraduate student to fill a position in Gene Therapy Process Development Department. The intern will work in part of a team of Scientists/ Engineers working in a preclinical phase II or III drugs and will be expected to perform analytical assays and present research data within the department. This role will provide the intern an opportunity to learn and work on advanced laboratory techniques.


ESSENTIAL FUNCTIONS:

• Design and perform purification of scalable proteins, knowledge of protein chemistry, preparative chromatography, and membrane separation techniques.
• Perform protein purification using AKTA Pure/AKTA Avant/AKTA Ready using Unicorn software.
• Isolation and purification using Dead end filtration and TFF.
• Purified sample analysis using SDS-PAGE, HPLC, ELISA and ddPCR/qPCR methods.
• Maintain and stock lab chemicals and consumables, buffer preparations and general lab duties.

EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

• Actively pursuing a B.S. degree in Life Sciences such as Biochemistry, Biotechnology, Biochemical Engineering, or other related biology or biological sciences. M.S. student preferred.
• 0-1 year of relevant laboratory experience in an academic research laboratory or biotechnology company.
• Ability to work in a team-oriented environment with good documentation skills.
• Strong computer skills with MS Office, scientific creativity, and collaboration with others.

OTHER QUALIFICATIONS:

• Experience in laboratory techniques supporting protein purification
• Solid understanding and experience with gene-editing techniques currently used for gene therapy products.
• Experience and understanding with cell culture system using insect cells and human cells

Any questions, please feel free to contact us here.


Sangamo is an equal opportunity employer
The above reflects management’s definition of essential functions for this position but does not restrict the tasks that may be assigned. The above duties are representative only; management may assign or reassign duties and responsibilities to this position at any time.

COVID-19
Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role.  If you are unable to receive the vaccine, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. 

Note to External Recruiters: Please understand that we do not accept unsolicited resumes from any source other than from the candidates themselves. Any agency or independent recruiter must have a signed copy of our agency agreement before presenting candidates. Submission of unsolicited resumes without our signed agreement will not create any implied obligation on our part.