Senior Scientist, Vaccines

Pearl River, New York
Jan 10, 2022
Required Education
Position Type
Full time


This position is a laboratory based position within the Vaccine Research and Development - Formulation Development group. The individual will design, develop, and execute studies to support the development of stable, robust formulations for new vaccine antigen candidates including bacterial, and viral vaccines.  The individual will define suitable processes and steps for manufacturing scalable formulations.


  • The individual will develop and communicate an executable formulation development plan, which incorporates knowledge about the antigen (s), material availability and program timelines.
  • Design and execute targeted DS and DP formulation studies to support formulation development of vaccine antigen candidates within Vaccine Research and Development (VRD). Vet plans with management and work with the appropriate lines to secure the needed analytical characterization support.
  • May represent the Formulation Development group on cross -departmental program teams.
  • Design and prepare DP formulations for early research animal studies based on an in-vivo dosing plan that is provided.
  • As required, design lyophilization cycles and execute studies to develop stable lyo dosage form vaccine formulations.
  • As required, perform relevant biophysical and particle characterization of the prepared formulations, using techniques such as micro-flow imaging (MFI), dynamic light scattering (DLS), and zeta potentials. 
  • Analyze data coming from multiple sources and propose formulation study conclusions that drive decisions to be made. The individual will communicate the collective findings and propose follow on actions, in a clear and concise manner, as required. 
  • The individual is expected to execute assignments with limited direct supervision and have the ability to prioritize the program deliverables against other activities.  The individual should be able to coordinates activities with others both inside and outside their immediate group and should be aware of all related timelines or due dates.
  • Stay current with the scientific literature. Leverage existing knowledge appropriately, being mindful of potential patents.


  • PhD with 0-3 years’ experience in Pharmaceutics, Biochemistry, Life Sciences or related science
  • Experience in pharmaceutical development and sterile drug product manufacturing is preferable
  • Relevant experience in protein, conjugate, or biologics formulation development is essential
  • Experience in process development, process scale up, lyophilization is desirable
  • Experience using biophysical formulation characterization techniques such as DSC, DLS, KF, and particle sizing techniques is a plus
  • Must have good technical, organizational, and communication skills
  • Have an ability to troubleshoot issues and interpret data in the context of project needs


  • The individual should be able to perform the duties of the job which may include pipetting, sitting, and standing
  • Ability to perform mathematical calculations and ability to perform data analysis


Occasional travel might be needed based on business needs


Eligible for Relocation Package

Eligible for Employee Referral Bonus

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.

Research and Development