Senior Director Research Science

Company Summary:

Inozyme Pharma is a biotechnology company committed to developing novel medicines for the treatment of rare metabolic diseases characterized by mineral imbalances. We are singularly focused on developing new therapies for patients with devastating rare diseases.  The company was founded in 2016 with technology licensed from Yale University and is well financed by a premier syndicate of venture investors.  Inozyme Pharma is led by an experienced management team with a proven track record in rare disease drug development, regulatory approvals, manufacturing and operations.

Our employees are central to our ability to achieve our goals of helping patients. We’re looking for people to join our team who are collaborative, compassionate, resilient, and passionate about what we do.

Description:

Senior Director, Research

The candidate will lead the company’s Research group, including the management and direction of bioanalytical projects related to immunogenicity in support of clinical development of clinical candidates.

The candidate will be a key leader and drive research based on their deep understanding of mineral metabolism, bone biology and calcification disorders. The candidate will be an ambitious & accomplished scientist and drug discoverer and will lead a team responsible for leveraging the platforms to identify, and prosecute, novel therapeutic targets. They will have responsibility for setting the strategy and direction for projects from development of therapeutic hypotheses through to assay and model development, target ID and validation, and drug discovery. They will foster a collaborative team environment, champion innovative scientific concepts, and contribute to the overall success on Inozyme.

We are looking for an individual with a track record of accomplishments in leading drug discovery teams from target identification through delivery of clinical candidates and establishing bioanalytical assays for clinical development. They should be a skilled scientist and excellent communicator, innovative, and comfortable in a fast-paced, entrepreneurial environment.

The Sr. Director of Research will report directly to the CSO, oversee the R&D team’s activities, and work closely with the company teams on key initiatives.

Education/Qualifications:

Key Responsibilities

• Provide strategic and scientific leadership for the research lab
• Advance programs from exploratory biology to drug discovery, prosecuting multiple targets and therapeutic concepts.
• Advance novel science and generate new ideas to enable continuous innovation on how Inozyme can translate the novel area of Biology into therapeutics to treat rare calcification diseases and beyond.
• Lead efforts to establish key bioanalytical assays related to immunogenicity (i.e., neutralizing Ab, CRIM, isotype etc.)
• Supervise internal efforts as well as work with external vendor to drive experimental plans that inform and enable project progression.
• Lead and develop colleagues using effective coaching and mentorship to maximize performance, engagement, and scientific growth.
• Lead external research relationships with academic and commercial partners.

Requirements:

Key Requirements

• PhD in relevant area of biological science, with 10+ years of post-PhD experience (extensive experience in industry setting is a plus) focused on the biology of mineral metabolism, bone, and vascular biology.
• Direct experience and deep knowledge of a broad range of the biology of calcification disorders. Experience in the areas of bone diseases is a plus.
• Track record of achievement across discovery biology, from exploratory biology through to candidate nomination.
• Proven ability to lead research and collaborate effectively in a multi-disciplinary team setting.
• A strong record of accomplishment in the field, including publications, patents, and presentations.
• Excellent communicator, with the ability to clearly convey complex messages to any audience.
• Confident, execution-focused, team-oriented.

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Position

Full-Time - Boston

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‍To all recruitment agencies: Inozyme Pharma, Inc. does not accept agency resumes. Please do not forward resumes to our job’s alias, Inozyme employees or any other organization location. Inozyme is not responsible for any fees related to unsolicited resumes.