Senior Scientist, Biotherapeutic Discovery Analytics

Cambridge, MA
Jan 07, 2022
Required Education
Position Type
Full time


We are seeking a highly motivated senior scientist to join the Molecular Assessment and Profiling group in BioMedicine Design as part of large molecule therapeutic discovery efforts.  The candidate will have daily interactions with a team of creative and innovative scientists, working collaboratively to conduct rigorous scientific and drug discovery research. This individual will plan, execute, and provide in-depth biochemical and biophysical characterization of AAV viral vectors and AAV capsids. In addition, this person will work with the biophysics team to drive gene therapy innovation, novel assays, and technology development.

As a member of the drug discovery team, the successful candidate will work in a fast-paced environment and will be playing a significant role in the drug discovery process.


  • Apply creative thinking and scientific expertise to the analysis of viral vectors

  • Conceptualize and design experiments.

  • Perform quality and stability assessment of gene therapy candidates

  • Critically analyze and present experiment results across multiple teams spanning general to subject expert audiences

  • Member of therapeutic discovery teams

  • Provide scientific guidance and decisions to move projects along the drug discovery pipeline

  • Drive technology innovation; evaluate new technologies and instrumentations

  • Work closely with cross-functional teams including AAV production groups, mass spec, and development organization to plan and execute deliverables


  • A PhD with 0-3 years of relevant experience in Biochemistry, Biophysics or related discipline

  • A solid understanding of protein biochemistry and stability

  • Hands-on experience with various protein, and DNA characterization methods and analytical biochemistry techniques (for example cGE, SEC, MALS, DLS, AUC, qPCR, DNA gel)

  • Ability to multi-task multiple projects with overlapping timelines.

  • Excellent communication, presentation, and documentation skills


  • Prior experience in therapeutic drug discovery and biochemistry research

  • Prior experience with viral vectors and/or AAV analytics is desirable

  • Demonstrated track record of independent research and scientific publications in peer review journals

Other Job Details:

  • Last Date to Apply: January 31, 2022
  • Eligible for Employee Referral Bonus
  • Eligible for Relocation Package


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

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Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.

Research and Development