Senior Scientist, Biotherapeutic Discovery Analytics
- Employer
- Pfizer
- Location
- Cambridge, MA
- Start date
- Jan 7, 2022
View more
- Discipline
- Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- Genetown, Best Places to Work
ROLE SUMMARY
We are seeking a highly motivated senior scientist to join the Molecular Assessment and Profiling group in BioMedicine Design as part of large molecule therapeutic discovery efforts. The candidate will have daily interactions with a team of creative and innovative scientists, working collaboratively to conduct rigorous scientific and drug discovery research. This individual will plan, execute, and provide in-depth biochemical and biophysical characterization of AAV viral vectors and AAV capsids. In addition, this person will work with the biophysics team to drive gene therapy innovation, novel assays, and technology development.
As a member of the drug discovery team, the successful candidate will work in a fast-paced environment and will be playing a significant role in the drug discovery process.
ROLE RESPONSIBILITIES
Apply creative thinking and scientific expertise to the analysis of viral vectors
Conceptualize and design experiments.
Perform quality and stability assessment of gene therapy candidates
Critically analyze and present experiment results across multiple teams spanning general to subject expert audiences
Member of therapeutic discovery teams
Provide scientific guidance and decisions to move projects along the drug discovery pipeline
Drive technology innovation; evaluate new technologies and instrumentations
Work closely with cross-functional teams including AAV production groups, mass spec, and development organization to plan and execute deliverables
BASIC QUALIFICATIONS
A PhD with 0-3 years of relevant experience in Biochemistry, Biophysics or related discipline
A solid understanding of protein biochemistry and stability
Hands-on experience with various protein, and DNA characterization methods and analytical biochemistry techniques (for example cGE, SEC, MALS, DLS, AUC, qPCR, DNA gel)
Ability to multi-task multiple projects with overlapping timelines.
Excellent communication, presentation, and documentation skills
PREFERRED QUALIFICATIONS
Prior experience in therapeutic drug discovery and biochemistry research
Prior experience with viral vectors and/or AAV analytics is desirable
Demonstrated track record of independent research and scientific publications in peer review journals
Other Job Details:
- Last Date to Apply: January 31, 2022
- Eligible for Employee Referral Bonus
- Eligible for Relocation Package
#LI-PFE
Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.
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