AbbVie

Scientific Associate III - Protein Science

Employer
AbbVie
Location
Irvine, California
Posted
Dec 07, 2021
Ref
2119364
Required Education
Bachelors Degree
Position Type
Full time
About Allergan Aesthetics
At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit www.AllerganAesthetics.com.

Allergan Aesthetics R&D, Biological Research is seeking a highly motivated and innovative candidate for the role of Scientific Associate III, Protein Science. The successful candidate for this position will work independently and contribute expertise to projects aimed at generating protein-based therapeutics. He/she will perform molecular biology techniques (PCR, Gibson assembly, ligase dependent cloning, site-directed mutagenesis) to support the group’s protein engineering efforts.  He/she will implement a variety of chromatography strategies (IMAC, IEX, SEC, HIC) to purify proteins from bacterial expression systems utilizing AKTA systems.  Additional protein research will include analysis by SDS-PAGE, Western blot and ELISA to evaluate the activity and functionality of therapeutic proteins. This individual will organize, analyze and interpret results, come forward with recommendations or understanding of the results, and communicate and present in team meetings and reports. The ideal candidate will be able to propose and design assays and have exceptional troubleshooting skills. Experience with protein/enzyme characterization including DLS/aggregation, HPLC (reverse phase/ size exclusion) and enzyme assays is desirable.  

The position is an entry level position in the scientific track at Allergan working on moderately complex assigned research projects.  Experimental design will be guided in consultation with management, but the candidate is expected to conduct experiments with substantial independence.  The candidate is expected to participate in discussions and decisions regarding the design of experiments and with assistance can develop modified or new techniques for conducting experiments.

Furthermore, the position requires you to work with and in areas requiring select agents and Toxins access (i.e. Biosafety level 2 and biosafety level 3 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, you must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements.  AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements, and objectives.

Responsibilities:

  • Independently conduct experiments of moderate complexity, designing the work plan so that reliable results are achieved in a timely manner.
  • Plan experimental approaches with supervisory guidance.  Discuss, recommend, and modify experimental techniques as needed.
  • Document and interpret results in order to reach conclusions, discuss with supervisor and decide on subsequent experiments.
  • Management of laboratory supplies and equipment needed for research (ordering supplies, equipment maintenance, record keeping, and inventory).
  • Develop and maintain up-to-date knowledge and skill base by reviewing the literature, attending seminars and meetings.
  • Prepare technical reports, presentations, and appropriate documentation of work performed.  Assist supervisor in maintaining project documentation.
  • Prepare technical reports, presentations, and appropriate documentation of work performed.  Assist supervisor in maintaining project documentation.

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Qualifications
  • Bachelor’s degree in Molecular Biology, Biochemistry or related life science field and 2 – 4 years relevant experience in cloning, protein expression, protein purification and characterization. 
  • Working Knowledge of molecular biology techniques (PCR, seamless cloning, ligase dependent cloning, primer design)
  • Hands-on experience with AKTA FPLC purification systems.
  • Experience with protein/enzyme characterization including SDS-PAGE, western blots, ELISAs
  • Excellent oral and written communication skills required as is experience with documentation of experimental plans, analyzing data and generating high quality technical reports
  • Experience in data analysis and graphing software
  • Skilled in chemical principles, theories, techniques and concepts, especially as applied in the laboratory.
  • Good interpersonal and organizational skills required.

Significant Work Activities
N/A
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
IC
About AbbVie
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.