Research Associate/Senior Research Associate, RESEARCH: T CELL IMMUNOLOGY, CAR T CELL
- Employer
- Adicet Bio, Inc.
- Location
- Menlo Park, CA
- Start date
- Dec 6, 2021
View more
- Discipline
- Regulatory, Science/R&D, Research, Immunology
- Required Education
- Bachelors Degree
- Position Type
- Full time
Job Details
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Adicet Bio, Inc. is a biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer and other diseases. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors and T cell receptor-like antibodies to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. For more information, please visit our website at http://www.adicetbio.com.
Research Associate/Senior Research Associate, RESEARCH: T CELL IMMUNOLOGY, CAR T CELL
We are seeking a highly motivated candidate with a research background in immunology to join the Adicet Research Team. The ideal candidate will have in-depth knowledge of T cell immunology and CAR-T cell development. The candidate will work as a part of a multidisciplinary team, utilizing the latest technologies for cell engineering and contributing to the generation of novel cell-based therapeutics for the treatment of cancer.
Responsibilities:
- Design, perform, and analyze in vitro experiments to characterize CAR-T cell function
- Cell culture (primary cells, cancer cell lines, CAR-T cells) for cell-based assay development (proliferation, cytokine release, cytotoxicity)
- Apply nucleic acid, protein, and reporter-based technologies (e.g., Nanostring, Luminex, Incucyte) for assay analysis
- Perform multi-color flow cytometry (cell surface/intracellular staining, cell sorting)
- Maintain detailed records of experimental protocols, results, and inventory in an electronic lab notebook
- Analysis and interpretation of experimental data
- Present at group meetings
- Utilize software tools to support data analysis tasks (e.g., Prism, FlowJo, Word, Excel and PowerPoint)
Qualifications:
- BS or MS in biological sciences or a related field
- 2+ years of relevant industry experience
- Experience in primary cell culture and aseptic tissue culture techniques is required.
- Experience with cell-based assays (e.g., CAR-T and cancer cell co-culture cytotoxicity, cytokine, proliferation, and serial stimulation assays)
- Experience with multicolor flow cytometry and data analysis on FlowJo is a plus.
- Ability to work collaboratively, multitask and meet deadlines in a fast-paced environment
- Openness to flexible working hours is preferred
- Organized and disciplined record keeping is essential
- Team player with excellent verbal and written communication skills
Benefits:
Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.
Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
Company
Adicet Bio, Inc. is a privately held, pre-clinical stage biotechnology company developing novel universal immune cell therapies based on gamma delta T cells engineered with Chimeric Antigen Receptors. Adicet is also focused on identifying and validating cancer specific targets directed to the intracellular proteome and then generating T Cell Receptor-like monoclonal antibodies (TCRLs) directed to these cancer-specific peptide targets presented by MHC Class I complexes. These TCRLs are being used to arm T cells or as T cell engagers in solid tumors. In August 2016, Adicet entered into a strategic collaboration with Regeneron Pharmaceuticals, Inc. to develop next-generation engineered immune-cell therapeutics using Adicet's gamma delta T cell allogeneic platform technology.
For more information, please visit our website at http://www.adicetbio.com.
- Website
- http://www.adicetbio.com/
- Mini-site
- Adicet Bio, Inc.
- Location
-
Adicet Bio
200 Constitution Drive
Menlo Park
California
94025
US
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