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Senior Research Associate, RNA Technologies

Employer
Intellia Therapeutics
Location
Cambridge, MA
Start date
Dec 4, 2021

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Job Details

Why Join Intellia? 

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. 

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. 

We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.   

How You Will Achieve More With Intellia:

Intellia is seeking a highly skilled and motivated Research Associate/ Senior Research Associate to join our RNA Technologies team. This is a position with a primary focus on executing characterization of mRNA and executing synthesize mRNA and purification for our lead Crispr/Cas9 gene editing programs. The ideal applicant will be able to follow SOP to execute mRNA characterization and to carry out mRNA synthesis by enzymatic method as necessary. Experience with oligonucleotide analysis and/or enzymatic and/or synthesis, basic analytical chemistry and nucleic acid biochemistry is preferred.

  • Execute on analytical testing of pre-clinical materials (mRNA)

  • As needed, execute enzymatic mRNA synthesis and purification

  • Build analytical characterization tools for process analytics

  • Provide high quality data to drive decision making in the team

  • Conduct, troubleshoot, and modify experiments to reach desired goals

  • Work independently in collaboration with colleagues in support of project goals

  • Provide high quality data and ELN documentation to drive decision making across different internal teams

  • Operate and maintain multiple laboratory instruments

  • Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies

About You:

Bachelor’s Degree in Analytical Chemistry, Chemistry, Biochemistry or related field with at least 2-5 years or Master's Degree with 0-2 years of industry experience

  • Able to develop and execute analytical SOPs for biochemical and molecular biology-based assays

  • Able to work with analytical chemistry such as U/HPLC-based methods

  • Experience with assay development for biomacromolecules (e.g. cell-based activity and potency, electrophoresis, enzyme reactions, and/or qPCR)

  • Familiarity with purification of DNA and RNA, and ideally proteins

  • Ability to multitask and handle a diverse array of challenges

LI#DG1

Covid-19 Vaccination Policy: Effective Monday, January 3, 2022, all Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Company

Many of us pursuing work in the biotechnology industry are inspired by a loved one who is living with a disease or the loss of someone in our community. Rare genetic and oncological and immunological diseases not only affect the people living with often debilitating and life-threatening symptoms, but these disorders also significantly impact their families, friends and caregivers.
 
Our researchers work tirelessly to harness the genome editing technology CRISPR/Cas9 for human therapeutic use. Jennifer Doudna, an Intellia co-founder, and Emmanuelle Charpentier were awarded the 2020 Nobel Prize in Chemistry for their pioneering work in CRISPR. We at Intellia are humbled to have a hand in making what we believe to be medical history. As a leader in this space, we take this responsibility to patients seriously.
 
We are employing a modular genome editing platform to create diverse in vivo and ex vivo pipelines, spanning a range of therapeutic indications. Guided by this full-spectrum approach, we are committed to making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to creating novel engineered cell therapies for various cancers and autoimmune diseases.

Change life stories with genome editing therapies!

Stock Symbol: NTLA

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Company info
Website
Phone
(857) 285-6200
Location
40 Erie Street
Cambridge
Massachusetts
02139
United States

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