Senior Scientist - Precision Oncology

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of. Join us.

Senior Scientist - Precision OncologyLive

What you will do

Lets do this. Lets change the world. Job Description

The Department of Oncology Research at Amgen, Thousand Oaks seeks an exceptional and motivated cancer biologist to lead collaborative teams focused on the discovery and development of novel targeted small molecule oncology therapeutics. The candidate will be part of a highly collaborative cross functional drug discovery team encompassing cancer biology, functional genomics, medicinal chemistry and structural biology.

In this vital role the senior scientist will manage a small research group, lead and support project teams from target nomination, lead candidate discovery through to phase 1 studies. In addition, the successful candidate will be expected to initiate novel programs, contribute to therapeutic area strategy and establishment of new discovery platforms, and maintain an external scientific presence.

Key responsibilities will include:

• Taking a leading role in new target identification and validation using genomic approaches such as CRISPR to assess gene function.
• Participation in the analysis of large-scale genomic, and phenotypic datasets e.g. DepMap
• Taking a lead role in cross-functional teams evaluating the pharmacodynamic activity, efficacy and mechanism of action of therapeutic candidates in preclinical oncology models.
• Close collaboration with our biomarker scientists to develop and implement pharmacodynamic assays and patient stratification strategies for programs transitioning to clinical development.
• Partner with colleagues in the oncology therapeutic area, bioinformatics and medicinal chemistry to develop our strategy and new technologies to enable the successful execution of our drug discovery goals
• Represent project teams through presentations at internal and external forums and the submission of manuscripts for publication.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Senior Scientist with these qualifications.

Basic Qualifications

Doctorate degree and 2 years of cancer biology or a related field

Or

Masters degree and 5 years of cancer biology or a related field

Or

Bachelors degree and 7 years of cancer biology or a related field

Preferred Qualifications

• PhD and post-doctoral training in cancer biology or a closely related field, preferable with a minimum of 3-5 years postdoctoral experience in an academic or industry setting.
• Broad knowledge of cancer biology, with demonstrate evidence of scientific independence and leadership through senior author publications in top-tier journals.
• Direct experience in new target identification and validation
• Research experience with state of the art molecular and cell biology techniques, particularly those relevant for assaying gene function (e.g. CRISPR or shRNA
• Experience leading drug discovery programs, and a proven ability to work effectively in a cross functional environment would be a plus.
• Strong organizational, interpersonal and communication skills
• Desire to be a team player in a dynamic, cross-functional environment

Thrive

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

• Vast opportunities to learn and move up and across our global organization
• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.