Computational Scientist, Machine Learning

ROLE SUMMARY

Pfizer Simulation and Modeling Sciences (SMS) group has an opening for a computational methods developer with expertise in molecular modeling, machine learning (ML), and scientific programming. The successful candidate will develop and deploy molecular modeling techniques, ML models, and computational tools to support mRNA based therapeutic efforts across Pfizer.

ROLE RESPONSIBILITIES

• In collaboration with key stakeholders across Pfizer R&D, develop state-of-the-art molecular modeling techniques, ML models, and computational tools to support mRNA therapeutics efforts. Specific tasks include, but not limited to, development of computational approaches to predict mRNA degradation and methods to improve their stability through efficient sequence optimization.
• Leverage proprietary computational framework and applications to deploy computational methods and ML models for wide usage by Pfizer scientists.
• Occasionally contribute to the ongoing and new method development efforts within SMS focusing on small molecule and biotherapeutics lines.
• Proactively identify, assess, and internalize promising methods and tools from external publications.
• Communicate and explain computational models and ML algorithms to broad scientific audience from diverse discipline.

BASIC QUALIFICATIONS

• Ph.D. in computational chemistry, physical or biological sciences, chemical engineering, computer science, or related discipline.
• Proficiency in general molecular modeling techniques.
• Proficiency in high-level programming language (e.g. Python); experience with Unix/Linux, HPC environments.
• Experience with machine learning.
• Strong track record of publications demonstrating applications of molecular modeling and/or ML to problems of pharmaceutical interest.
• Excellent communication and interpersonal skills.

PREFERRED QUALIFICATIONS

• Experience in applying molecular modeling and/or ML to mRNA design and optimization.

  Additional Job Information:

• Eligible for employee referral bonus
• Eligible for relocation support

#LI-PFE

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.

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