Research Associate - Scientist: Molecular Structure-Function

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Adicet Bio, Inc. is a biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer and other diseases. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors and T cell receptor-like antibodies to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. For more information, please visit our website at http://www.adicetbio.com.

RESEARCH ASSOCIATE - SCIENTIST: MOLECULAR STRUCTURE-FUNCTION

Overview:
Adicet Bio is seeking motivated individuals at Research Associate through Scientist levels to advance gamma delta CAR-T development by working at the interface of antibody discovery and cell therapy development. The ideal candidate will be creative, excited to learn, and enjoy working in a collaborative environment that provides huge growth potential.

Key Responsibilities:

• Work collaboratively with teams across the Research department on new target development projects in immuno-oncology 
• Development/optimization/execution of immune cell-based assays for in vitro functional studies, including T cell-based screening of CAR candidates
• Characterization of antibodies to tumor associated antigens (binding, specificity, epitope binning) using biophysical and cell-based assays 
• Data generation, data analysis, and communication to immediate team and cross-functional teams

Qualifications:

• BS or MS in Biology, Biochemistry, Immunology and related disciplines 
• 1-5+ years of relevant academic and/or industry experience
• Broad technical expertise working with antibodies and cell therapies is a plus
• Hands-on tissue culture experience is required (maintaining cell lines, freezing and thawing cells, experience with primary cells is a plus)
• Experience with cell-based assays such as T cell proliferation, activation, in vitro cytotoxicity assays 
• Hands-on experience with multi-color flow cytometry 
• Hands-on experience with fluorescence and luminescence-based readouts using a plate reader
• Experience characterizing antigen-antibody binding by ELISA/Octet/SPR/Flow cytometry is a plus
• Experience with immune cell phenotyping using high dimensional mass-cytometry (CyToF)/CyToF analysis is a plus
• Ability to multitask and meet deadlines in a fast-paced environment
• Excellent verbal and written communication skills

Benefits:

Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.