Sr Research Scientist II, Biomarker

Location
Foster City, CA
Posted
Nov 26, 2021
Ref
2667780
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Sr Research Scientist II, Biomarker
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible


Senior Research Scientist II - Biomarker Sciences Oncology

This position is open to Seattle or Foster City locations.

The Biomarker Sciences department is seeking an experienced Senior Research Scientist II (SRSII; Associate Director equivalent) in the Oncology therapeutic area. The SRSII will be responsible for leading the clinical biomarker efforts for Magrolimab, a first-in-class, investigational anti-CD47 monoclonal antibody, in one or more solid tumor indications. Magrolimab has received FDA Breakthrough Designation and is being developed in a range of malignancies.

Responsibilities:

  • Lead cross-functional Biomarker Teams in the execution of clinical biomarker and diagnostic strategies
  • Collaborate with Clinical Development, Research Biology, and Clinical Data Sciences to generate, analyze, and interpret data from clinical trials and human translational studies
  • Oversee the development, validation, and outsourcing of biomarker assays testing specific hypotheses related to pharmacodynamics, MOA, patient response, and/or safety
  • Provide expertise to project teams on appropriate biomarker and diagnostic technologies, including their scientific basis, clinical applicability, and technical or statistical considerations
  • Author biomarker-specific documents, and contribute to clinical protocols and regulatory submissions
  • Maintain knowledge of relevant scientific advances and the competitive landscape
  • May involve management of direct reports


Technical Skills:

  • Demonstrated expertise in oncology and/or immunology, with strong scientific background in hypothesis-driven research and demonstrated ability to design, execute, and interpret experiments
  • Experience in implementation of biomarker strategies in clinical stage programs; strong understanding of clinical development in solid tumors, particularly immuno-oncology, preferred
  • Knowledge of biomarker discovery, assay development and validation, and translational research
  • Proven ability to work independently as well as demonstrate leadership in a team environment
  • Excellent writing, verbal communication, and presentation skills
  • Must be motivated, strategic, impact-focused, and enjoy working in a demanding environment


Experience:

PhD and/or postdoctoral training immunology, cancer biology, or related medical science, and 5+ years of relevant biopharma industry experience required. Title will be dependent on experience.


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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

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