Sr Associate Scientist, Inflammation Biology

Location
Foster City, CA
Posted
Nov 26, 2021
Ref
2667544
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Sr Associate Scientist, Inflammation Biology
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible


We are seeking a highly motivated Senior Associate Scientist to join our inflammation group. The candidate will be responsible for evaluating novel inflammatory therapeutics in pre-clinical models of rheumatoid arthritis, lupus, autoimmune encephalomyelitis, and colitis. Hands on experience and substantiated knowledge with preclinical models of inflammatory autoimmune diseases is required. The successful candidate will be responsible for designing, generating and communicating pharmacology data of preclinical models internally to support inflammatory target discovery for autoimmunity. Title will commensurate with industrial experience and previous track record of research article/patent publication.

Primary responsibilities:

  • Designing, conducting, analyzing and reporting in vivo studies (efficacy, PK/PD)

  • Pre-clinical model development, optimization, and characterization

  • Interface with cross-functional project team members, and participation in and presentation at project team meetings and cross-departmental team meetings

    Qualifications & prior experience:

  • BS/MS degree in Biology or Pharmacology related discipline

  • Minimum 10+ years of research experience in an industry setting and good understanding of inflammatory disease pathogenesis. Note: Level will commensurate with experience

  • Research experience with at least 1-2 mouse models of inflammatory animal models including but not limited to collagen induced collagen induced arthritis, autoimmune encephalomyelitis, OVA induced asthma, and/or experimental colitis

  • Proficiency with various mouse handling techniques including dosing (IV, PO, subcutaneous, IP), preclinical manifestation scoring (e.g., joint swelling, paralysis), and collection and handling of tissues during necropsy and processing for ex vivo analysis

  • Experience with lymphocyte FACS sorting, magnetic bead-based cell isolation, and flow cytometric analysis are highly preferred

  • Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word

  • Excellent organizational and communication skills, along with the ability to work effectively in a multidisciplinary team environment

  • The ability to work independently on day-to-day responsibilities and research goals

    For jobs in the United States:

    As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

    Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S. employees and contractors to receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.​

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