Research Associate, Genomics

Cambridge, MA
Nov 25, 2021
Required Education
Bachelors Degree
Position Type
Full time

About the Role:

Omega Therapeutics, Inc. is seeking a Research Associate to join our integrated Computational Genomics & Data Sciences group as a key contributor in our functional genomics efforts. The successful candidate will be an essential member of a close-knit team of experimental and computational scientists driving Omega’s platform technologies and supporting a broad set of therapeutic programs. We are looking for enthusiastic, detail oriented, adaptive, and highly motivated individuals with a passion for bringing novel medicines to patients and who are comfortable working on a fast-paced cross-functional scientific team.

Key Responsibilities:

  •  Execution of NGS-based functional genomics assays that address core R&D needs in cell state mapping and therapeutic molecular validation
  • Collaborate across platform and program teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies
  • Assist in plasmid design, cloning, and execution of specialized molecular assays; generate and maintain mammalian cell lines when needed
  • Maintain lab organization and inventories for NGS-related workstreams

 Required Skills:

  • Adaptive and detail-oriented with excellent time management and organizations skills
  • Exposure to molecular biology techniques, including functional genomic NGS assays (e.g. RNA-seq, ChIP-seq, ATAC-seq, etc.)
  • Familiarity with NGS library processing and operation of Illumina instruments preferred
  • Exposure to high-throughput automation technologies, such as Tecan liquid handing preferred
  • Familiarity with cell-based assays such as flow cytometry, western blot, qPCR, ELISA, etc. preferred
  • Exposure to CRISPR-based or other gene editing technologies preferred
  • Working knowledge and understanding of epigenomic gene regulation
  • Exceptional teamwork and communication skills

Required Qualifications:

  •  BS/BA or MS in Cell or Molecular Biology, Biochemistry, or related fields
  • Experience in academic or industrial labs preferred