Senior Research Associate or Research Scientist

Location
San Francisco, CA
Posted
Nov 25, 2021
Ref
REQ-1104
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Category:Science
Lab/Area:Finkbeiner Lab

Description:

We are seeking a highly motivated candidate for a Senior Research Associate or Research Scientist to work in a dynamic, collaborative environment using cutting edge methods and technology to unravel neurodegenerative diseases. The successful candidate will help drive the scientific goals and objectives of several projects to using high throughput, human models of neurological disorders such as Amyotrophic Lateral Sclerosis (ALS) and Huntington’s Disease (HD). This person will have experience using CRIPSR, induced pluripotent stem cells (iPSCs) and imaging. Using these tools, you will help orchestrate and execute a platform to model the process of neurodegeneration. This role is very diverse, multidisciplinary and dynamic. You will work closely with our software engineers using machine learning (ML) or other approaches to phenotype disease signatures from patient cells.At the heart of our lab is a novel robotic microscopy (RM) system that can track numerous molecular features of cells over time (an example of how RM is used is found here).  RM allows us to extract various types of biological information about how cells grow, mature and behave in response to candidate drugs or genetic perturbations. We then use ML approaches to extract features from our iPSC models to help identify and distinguish disease phenotypes.We have collaborations with many industry and academic groups, publish our work in high profile scientific journals, and present our work at international conferences. We are looking for candidates with the desire to learn and work on a fast-paced project. The ideal candidate will have experience with managing others, designing and overseeing experiments from start to finish, growing and differentiating iPSCs, and some experience using R or python.

Education/Skills Experience Required:

  • 9+ years of related exp for individuals with an AA/AS
  • 7+ years of related experience for individuals with a BS/BA
  • 5+ years of related experience for individuals with a MS/MA
  • 0 years of related experience for individuals with a PhD
  • Or an equivalent combination of education and experience
  • Degree should be in the field of Biological Sciences or Engineering.
     

 Education/Skills Experience Preferred:

  • PhD in a field of Biological Sciences or Engineering.
     

Skills/Experience required:

  • Critical thinking and ability to design and execute experiments independently
  • Highly organized and strong data analysis expertise
  • Excellent communication and interpersonal skills
  • Team player
  • Molecular and cell biology expertise
  • Self-driven and passionate about science
  • At least 4 years research experience in research biology
  • Widefield and/or confocal microscopy experience
  • This candidate must have previous cell culture experience at a minimum of 2 years
     

Skills/Experience preferred:

  • Experience in R or Python
  • iPSC culturing and differentiation into specific cell types
  • Experience in leadership and mentorship of others 

Additional Information:
  • Title and salary will be commensurate with education and experience.
  • Be a part of big ideas and consider Gladstone. Your difference will make a difference in human health.
  • Gladstone is an equal opportunity employer.