successful candidate will join a highly motivated team of scientists and
associates developing novel genetic therapies for respiratory diseases and will
be responsible for development and execution of bioanalytical assays to support
Develop and execute robust
bioanalytical assays to support cell-based and in vivo studies. These
assays will focus initially on detection and quantitation of target
protein expression and mRNA cargo as well as immunogenicity and
tolerability of the drug candidates.
Work closely with cell culture,
in vivo, RNA production, and formulation teams to coordinate sample
processing and bioanalytical assays.
Will be expected to collect and
analyze data, and prepare technical reports, summaries, and presentations
to the department and key stakeholders.
Must be able to maintain accurate
and well-organized laboratory records, worksheets, and notebooks.
BS/MS with 3+ years of industry
experience preferably in a development (Bioanalytical, QC) environment.
Hands-on experience with design,
development, optimization, qualification, and validation of novel
bioassays and immunoassays using multiple platforms and technologies (e.g.
ELISA, MSD/Luminex, flow cytometry, cytokine analyses, and cell-based
reporter and cytotoxicity assays).
Strong foundation in molecular
biology and experience with gene expression analysis methods (e.g.
Quantitative RT-PCR, ddPCR).
Experience with protein
analytical methods (SDS-PAGE, Western Blotting).
Experience with sample processing
methods to support protein and nucleic acid detection from a variety of
Excellent skills in Microsoft
Office, data analysis software (e.g. Prism, JMP, FlowJo, FACSDiva, SoftMax
Pro), and other applications.
Must be comfortable in a fast-paced
small company environment with minimal direction.
Self-starter with excellent
interpersonal skills and demonstrated success working with
multi-disciplinary teams in a matrix environment.
Strong oral and written
communication skills to support internal and external communications/presentations.