Senior Scientist, Bioinformatician - Computational Immunology

Location
Redwood City, California
Posted
Nov 19, 2021
Ref
R1550225
Hotbed
Biotech Bay
Required Education
Doctorate/PHD/MD
Position Type
Full time

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science.In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

JOB DESCRIPTION

We are seeking a creative and collaborative bioinformatician with expertise in computational immunology to help us discover and develop the next generation of therapeutic antibodies and cellular therapies. You will be responsible for designing and implementing novel computational approaches on next-generation sequencing (NGS) data to identify B-cell and T-cell receptor sequences that can be optimized for protein and cellular therapeutics with desired binding characteristics and biological activity. This role provides the opportunity to work on multidisciplinary teams to solve challenging problems in the discovery and design of new biological and cellular therapies. We are deeply passionate about what we do here at Bristol Myers Squibb because we know that our work helps deliver truly innovative and life-changing therapies for complex diseases of unmet medical need. If this inspires you as well, were excited to have you join us!

RESPONSIBILITIES

  • Develop and apply immunosequencing analysis strategies for assessing potential binding targets, biophysical characteristics, and biological activity
  • Partner with project teams to build pipelines around analytical frameworks for antibody and T-cell receptor repertoire sequencing
  • Collaborate with colleagues as part of project teams passionate about developing the next generation of innovative therapeutic antibodies and cell therapies, lending analytics expertise to biological and technical domain matter experts as required
  • Present strategies, approaches, results, and conclusions to a publishable standard in static and interactive formats
  • Stay informed on the latest research in bioinformatics methods and analyze their potential impact on our capabilities
  • Participate in authorship of scientific reports, and present methods and conclusions to publishable standards

QUALIFICATIONS

  • PhD in structural bioinformatics, computer science, engineering, statistics, or similar with 2+ years of post-doctoral work or relevant industry experience.
  • Demonstrated ability to derive insights from high-dimensional data with complex patterns using statistical learning approaches using readable, reproducible, and efficient code.
  • Proven track record of contributing to and helping advance multi-disciplinary team projects.
  • Expertise in algorithmic implementation, workflow/pipeline development, statistical programming and data manipulation using middle-level languages or Python/R; contemporary, open-source bioinformatics tools and database structures, collaborative development skills using version control systems (e.g., Git), familiarity with Unix shell and deployment and use of virtualized working environments (e.g., Docker).
  • Scientific curiosity with an ability to identify questions bioinformatics approaches can address, and the skills to develop solutions both independently and collaboratively.
  • Excellent problem-solving skills and teamwork.
  • Strong communication, data presentation, and visualization skills.
  • Knowledge in biochemistry or protein engineering is a plus.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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