Scientist I/II

Manager: Senior Scientist
Department: Research
Location: Richmond, CA

Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms – gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and proprietary zinc finger genome engineering technology, Sangamo is working to create genomic cures for patients suffering from severe genetic diseases for which today’s medicines can only treat symptoms. At Sangamo, we are passionate about transforming lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise.

JOB  SUMMARY: 

 We are seeking a talented scientist to support the development of new genomic medicines. The successful candidate will work within a team of dedicated researchers designing cutting edge genome editing and gene regulation technology to treat genetic diseases. This is a highly-collaborative, hands-on position at the interface of discovery and translational research activities. The position requires a strong background in molecular biology, adaptability, creativity, good written and verbal communication skills, and a capacity for constant innovation in pursuit of company goals. The environment is fast-paced and offers the opportunity to work at the leading edge of genome engineering research and translational medicine.

ESSENTIAL FUNCTIONS:                                                                                               

• Work with a senior scientist to design novel genome editing reagents utilizing Sangamo’s vast array of proprietary zinc finger reagents
• Plan and execute in vitro experiments for reagent characterization
• Generate proof-of-concept data to support the advancement of novel therapies towards IND
• Manage and support research studies with academic partners and/or contract research organizations
• Closely collaborate with a small team of talented senior level research associates and members of the discovery, technology, delivery and nonclinical teams
• Present results internally to R&D and executive leadership teams and externally at scientific conferences
• Publish results in leading scientific journals and contribute to related patent filings

EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

• Ph.D. in Molecular Biology, Immunology or related discipline
• 0 - 2 years  of relevant industry or post-doctorial experience for Scientist I. 2+ years of relevant industry or post-doctoral experience for Scientist II.  Level will be determined by experience, skills, and ability.
• Experience using gene therapy or genome editing tools
• Proficiency in mammalian tissue culture, preferably primary hepatocytes and/or hematopoietic cell lineages
• Expertise in molecular and biochemical methods (PCR, flow cytometry, ELISA, western blotting, next gen sequencing, and molecular cloning)
• Working knowledge of viral vectors (AAV or LV) is a plus
• Experience working on epigenetic or gene regulation technologies is a plus
• Experience with flow cytometry or cell-based functional assays is a plus

OTHER QUALIFICATIONS:

• Ability to work in a team-oriented, multidisciplinary environment
• Ability to lead a project team as well as work independently
• Strong written and oral communications skills

Sangamo is an equal opportunity employer
The above reflects management’s definition of essential functions for this position but does not restrict the tasks that may be assigned. The above duties are representative only; management may assign or reassign duties and responsibilities to this position at any time.

Commitment to Safety

Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role.  If you are unable to receive the vaccine, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. 

Note to External Recruiters: Please understand that we do not accept unsolicited resumes from any source other than from the candidates themselves. Any agency or independent recruiter must have a signed copy of our agency agreement before presenting candidates. Submission of unsolicited resumes without our signed agreement will not create any implied obligation on our part.

If you wish to be considered for the presentation of candidates, please contact us through Recruiting@sangamo.com. Attach your contact information, your area of specialty, and any marketing information you wish to provide. Someone form the Talent Acquisition Department will contact you directly if there is a business need for your services.

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