R&D Specialist (Therapeutic Antibody Discovery)

We are seeking a motivated research associate to join our human antibody isolation team which contributed to the development of Regeneron’s Sars-Cov2 antibody cocktail (REGEN-COV). The successful candidate will play an integral part in the identification of antibodies to treat diseases with unmet medical needs. The primary functions of this position are the isolation of monoclonal antibodies from human donors against diverse disease targets (eg. infections, immune disorders, etc) and the development of new antibody isolation technologies. The ideal candidate is a team player who is experienced with cell culture, is eager to learn and who will utilize cutting edge techniques for the development of the next generation of therapeutic antibodies.

A typical day may include:

• Isolating PBMCs from human peripheral blood

• Performing cell enrichment, cell culture, antibody staining and phenotypic characterization

• Independently designing, conducting, and analyzing multicolor flow-cytometry experiments

• Optimizing and carrying out functional assays such as ELISA

• Performing molecular biology experiments, including DNA/RNA purification, RT-PCR and molecular cloning

• Analyzing and presenting data in a team-based setting

• Maintaining complete, accurate, and timely records of experiments and data analysis

• Contributing to lab equipment maintenance and ordering supplies/reagents to help create a safe, effective, and efficient working environment

This role may be for you if:

• You can work in a collaborative fast paced working environment

• You have a strong desire to develop your skills

• You are an independent thinker and have problem solving abilities

• You excel at maintaining experimental documentation

To be considered for this position, you must have a BS+5 years or a MS+3 years of experience in Immunology, Biology, Biochemistry, or related discipline. Hands-on technical experience in cell culture and/or PBMC isolation, and flow cytometry is required. Knowledge of functional assays (ELISA, ELISPOT) is highly desired, but training can be provided if necessary. Experience with molecular biology techniques (DNA/RNA/qRT-PCR, cloning) is a plus.