Scientist, Cell Culture Development

Gaithersburg, Maryland
Nov 17, 2021
Required Education
Position Type
Full time

Medical Science & Computing (MSC), is searching for a Scientist, Cell Culture Development to provide support to the National Institutes of Health (NIH). This opportunity is a full-time position with MSC and it is on-site in Gaithersburg, Maryland.

Duties & Responsibilities
  • Actively participate and lead development projects for clinical vaccine candidates to include development of viral vaccines, recombinant proteins and/or virus-like particles, or monoclonal antibodies.
  • Produce research reagents using either transient expression techniques or by expansion of stable cell lines or pools.
  • Coordinate with and possibly work under the direction of the Cell Line Development Group to assure the availability of materials and supplies in a timely fashion, and to gather data and understand the process as much as possible.
  • Contribute to the Cell Culture Process Development group as a cell culture scientist to include experimental investigations on cell line behavior, optimization of cell culture conditions, tech-transfer of defined cell culture processes to the clinical production facility, improvement of cell culture platforms, troubleshooting of cell culture processes, and capturing process descriptions and results in tech transfer documents and technical reports.
  • Designing, proposing, and performing experiments in the area of cell culture process development, capturing and communicating the results in several formats, and working with technology transfer teams to move the developed processes into a clinical production facility.
  • Develop and maintain collegial, collaborative relationships with colleagues in the partnering lab research groups and Purification, Analytical, and Manufacturing to ensure that efforts are efficiently translated with other groups.
  • Assist in training and management of junior scientists.
  • Participate in project and laboratory meetings, staying current with the literature in the field.
  • Help assure the laboratory maintains its state of the art status.
  • Publishing results and studies in peer reviewed journals is encouraged.


  • Ph.D. in Biochemical/Chemical Engineering or related field with 0 - 3 years of experience or a M.S. in Biochemical/Chemical Engineering or related field with 6 – 10 years of experience in cell culture development is required.
  • Good oral and written communication skills are required.
  • Experience in writing and reviewing Batch Production Records, SOPs, and other process documents is highly beneficial as is mathematical modelling of cell culture processes.
  • Experience with mammalian cell culture for both anchorage dependent and suspension cell culture, with larger scale cell culture systems (bioreactors), with routine sampling and analysis of cell culture and bioreactor samples, and with media and cell culture technology development. Additional expertise in molecular biology and design of expression vectors, transfection techniques, and screening of cells expressing recombinant proteins will be useful.
  • Familiarity with statistical design packages (JMP, minitab, etc.) is required, as is the use of good laboratory practice and record keeping, the use of analytical tools and the following of protocols to acquire reproducible data, and the presentation of results in group meetings and in technical reports.
  • Works well in both individual and team settings, and provides significant leadership to the design and interpretation of experiments and the overall understanding of the process.
  • Familiarity with GMP and regulatory compliance.





Due to our contractual requirements and federal orders, including an Executive Order from the White House and an emergency regulation from the Centers for Medicare & Medicaid Services (CMS), the position for which you are applying requires that you provide proof of your vaccination status. If you are unable to receive the COVID-19 vaccine for medical reasons or because of a sincerely held religious belief, you may request an exemption from the vaccination requirement which shall be reviewed after the submission of requested documentation. If an accommodation is granted, the conditions may include weekly testing and masking. All Guidehouse employees also agree to follow any additional health and safety mitigation policies that may be required in the workplace.

Company Description

Dovel Technologies and its Family of Companies (Medical Science & Computing and Ace Info Solutions) were acquired in October 2021.


Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success. The company has more than 12,000 professionals in over 50 locations globally. Guidehouse is a Veritas Capital portfolio company, led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.


Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.


Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance, including the Fair Chance Ordinance of Los Angeles and San Francisco.


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