Research Associate, Discovery (High-throughput Mammalian Screening)
- Employer
- Mammoth Biosciences
- Location
- Brisbane, CA
- Start date
- Nov 17, 2021
View more
- Discipline
- Regulatory, Research/Documentation, Science/R&D, Research
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
Mammoth is currently seeking a creative and detail-oriented Research Associate with experience in molecular biology, next-generation sequencing, and/or mammalian cell culture to join our Discovery team.
The successful candidate will work collaboratively with colleagues to develop and execute high-throughput experiments in mammalian cell lines to support the discovery, characterization, and development of novel Cas nucleases for genome editing. They will have the opportunity to contribute broadly across multiple technical areas, including automation, software tool development, synthetic biology, and high-throughput screening.
This position requires adaptability, strong organizational and communication skills, and the ability to work both independently and collaboratively in a dynamic team-oriented environment.
KEY RESPONSIBILITIES
- Develop and execute high-throughput molecular biology, cell culture, and functional assay protocols in the novel Cas nuclease discovery and development pipeline
- Integrate high-throughput laboratory automation into experimental workflows
- Detailed, accurate, and timely documentation of experimental procedures, data, and analysis, including meticulous sample tracking and data management
- Provide team support for wet lab tasks including tissue culture of various cell lines, phenotyping and analytical characterization of cells, genome editing of human cells, etc.
- Regular communications of data and analysis results to senior staff and team members
- Conduct all activities in a safe and efficient manner, adhering to environmental health and safety requirements
REQUIRED QUALIFICATIONS
- Bachelor’s degree in molecular and cell biology, immunology, biochemistry, or a related field
- 1 year of research experience with mammalian cell culture or in molecular/cell biology
- 2 years of laboratory experience in the biotechnology industry
PREFERRED QUALIFICATIONS
- Experience or proficiency in mammalian cell culture, molecular cloning, PCR, DNA/RNA purification, and next-generation sequencing
- Experience with high-throughput laboratory automation (e.g. Tecan liquid handlers, Labcyte Echo, ZAG)
- Experience or proficiency with SQL, JMP, Python, etc.
- 3+ years of biotechnology industry experience
BENEFITS
- Company-paid health/vision/dental benefits
- Unlimited vacation and generous sick time
- Company-sponsored meals and snacks
- Wellness, caregiver and ergonomics benefits
- 401(k) with company matching
Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber.
TEAM
Our small-size proteins, such as Cas14 and CasPhi, are poised to transform disease treatment enabling novel editing approaches and delivery options that are difficult to achieve or not even possible with previously described CRISPR-Cas systems. Our teams are responsible for discovering and engineering novel CRISPR systems, establishing CRISPR-based diagnostics, and translating our unique CRISPR technology into therapeutic treatments with the ultimate goal of cures for indications with high medical need.
It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.
Company
Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.
- Website
- http://www.mammoth.bio/
- Phone
- (650) 294-8583
- Location
-
South San Francisco
CA
94080
United States
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