Scientist, Biology Assay Automation

Location
Boston, MA
Posted
Oct 27, 2021
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time

Scorpion Therapeutics is a precision oncology company founded in February 2020 by a preeminent group of scientists from Harvard University/Massachusetts General Hospital – Keith Flaherty, MD, Gaddy Getz, Ph.D. and Liron Bar-Peled, Ph.D. The company has raised $270M in Series A and Series B financings led by blue-chip investors, including Atlas Venture, Boxer Capital of Tavistock Group, EcoR1 Capital, LLC, Omega Funds, and Vida Venture.

Scorpion Therapeutics’ mission is to serve oncology patients by discovering and developing best-in-class and first-in-class, small molecule cancer medicines that address large patient segments with significant unmet medical needs. To accomplish this mission, we are building a highly collaborative team focused on the pursuit of novel approaches to small molecule drug discovery. This approach relies upon dynamic collaboration between cancer biology, proteomics, informatics, structural biology, and medicinal chemistry – with the ultimate goal of realizing the full potential of targeted/precision oncology.

We are seeking a highly motivated scientist to join our dynamic biology drug discovery team. This candidate will serve a critical role in leading the automation of cell-based, biochemical, and proteomic assays in support of our small molecule drug discovery programs. This position is ideal for a talented, highly motivated and results driven individual who will thrive in a fast-paced, innovative, start-up environment.

KEY RESPONSIBILITIES

  • Primary responsibility for operating, optimizing, troubleshooting, maintaining, and training personnel on HighRes automation suite.
  • Facilitate use of the automation suite by others to establish and run their own partially or fully automated cell-based and biochemical assays and screens.
  • Oversee the standardization of internal and CRO screening assay formats across functions.
  • Facilitate implementation of workflows for data processing and analysis (i.e. Scinamic, Egnyte).
  • Use decision making, organizational and communication skills to effectively collaborate with colleagues in Biology, Chemical Biology, Biochemistry and Medicinal Chemistry.
  • Consult on assay development and optimization for supporting target biology and drug discovery using a variety of approaches, including analysis of signaling pathways, and characterization of cell death mechanism(s) (i.e. HTRF, HiBiT, NanoBRET, CTG, Reporter Assays).
  • Present data and findings at various venues, including project team, department, and company meetings.

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

  • BS/MS in Biology or a related field.
  • 10 years of relevant laboratory experience with at least 5 years of experience running automated assays using HighRes or similar platform.
  • A deep and broad understanding of mammalian cell culture, cell-based and biochemical assay implementation, and data processing with excellent scientific rigor.
  • Commitment to the highest-quality research with outstanding organizational abilities and scientific execution.
  • A highly engaged, self-starter who is creative, innovative, communicative and possesses both a collaborative and goal/results-orientated style.
  • Desire to work in a fast-paced, multi-tasking environment, while employing tact, patience, diplomacy and a collaborative spirit.
  • The desire and ability to contribute to teams working on challenging scientific problems and first-in-class therapeutics.
  • A strong record of achievement, including contributing to drug discovery programs and publications is highly desirable.
  • Outstanding decision making, organizational and analytical skills.
  • Exceptional interpersonal and communication skills.

Scorpion Therapeutics Inc. is an Equal Opportunity Employer who strives to create and maintain a diverse working environment. We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.