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Scientist, Bioinformatics

Employer
Avidity Biosciences
Location
San Diego, California
Start date
Oct 19, 2021

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Job Details

Bioinformatic Scientist

Location: La Jolla, CA

Position type: Research and Development

Description:

The Development Sciences team at Avidity Biosciences in La Jolla, CA is seeking an experienced data/bioinformatic scientist to define and build the bioinformatics function at Avidity across preclinical and clinical research. The ideal candidate enjoys problem solving, has a passion for learning and teaching, and has used multi-dimensional data to visualize, elucidate and communicate drug mechanisms and disease pathophysiology. Proven ability supporting analysis of large and complex multi-omics data sets is required. He/She should enjoy scientific discovery and collaboration in a fast-paced interdisciplinary environment.

Responsibilities:

  • Develop/implement quality assessment methods, statical analysis and data visualization for multi-omics dataset (e.g., bulk RNAseq, WES, WGS, nanostring, multiplex qPCR)
  • Build the bioinformatics and data analysis pipeline/visualization infrastructure, data storage and analytical capabilities within Avidity
  • Design and apply bioinformatics/statistical algorithms, unsupervised and supervised methods, univariate and multivariate regression analyses, etc.
  • Serve as a resource for the most current data visualization, bioinformatics and statistical methods
  • Leverage his/her experience and skills in bioinformatics, biostatistics, and/or data science to support biomarker discovery and development efforts to elucidate drug MoA and disease biology to bring meaningful therapies to patients.

Requirements:

  • PhD in bioinformatics, statistics, computational biology or related discipline with minimum 2 years of relevant experience in pharmaceutical industry; Masters degree with at least 5 years of relevant experience will also be considered
  • Direct experience analyzing, interpreting, and integrating large-scale datasets is required (e.g., single-cell or bulk RNAseq, microarray or other genomic, transcriptomic, proteomic and/or other)
  • Strong knowledge of statistical methods for probability theory, statistical power, univariate and/or multi-variate analysis, unsupervised and supervised analysis, regression analysis and/or deep learning, etc.
  • Must be proficient in statistical and scripting programming language, such as R, RShiny, Python, Perl or other
  • Expertise developing/deploying algorithms and applications for predictive modeling, pattern recognition, machine learning, data mining and/or visualization of large scale multi-dimensional datasets will be needed

Desired Attributes:

  • Ability to communicate and collaborate effectively with other research scientists in a multidisciplinary and manage multiple projects in a fast-paced working environment
  • Ability to collaborate to synthesize scientific questions into clear, coherent analyses, iterate on requirements, visualize and communicate scientific findings to enable data driven solutions
  • Possess analytical/problem-solving skills with a drive for results and flare for visual representations of data
  • A proactive and self-motivated individual with a strong work ethic, ability to work in a dynamic environment and able to manage multiple objectives in parallel and adapt to changing priorities
  • Strong interpersonal skills and able to collaborate and work cross functionally

Avidity is committed to complying with federal, state and local law on employee vaccinations.  Job candidates should be aware that full vaccination against COVID-19: is required subject to legally required exceptions.  Avidity is an equal opportunity employer and will comply with responsible accommodations requested under federal, state and local regulations.


Company

avidity banner

Our vision is to profoundly improve people’s lives by revolutionizing the delivery of RNA therapeutics. We’re utilizing our proprietary AOC platform to design, engineer, and develop therapeutics that combine the tissue selectivity of monoclonal antibodies (mAbs) with the precision of oligonucleotide-based therapies in order to redefine RNA therapeutics and more effectively target underlying genetic drivers of diseases. We are delivering on this vision by investing in our platform, our pipeline and our people.

Our commitment to rigorous and innovative science is matched only by our passion to see patients’ lives changed. We consistently challenge ourselves to Be AVID – Agile, Visionary, Integrated and Diverse.

We are assembling a diverse team experienced in rare disease and RNA therapies. Our team members bring expertise in research, development and commercial execution. We are focused on cultivating the right team to not only grow the company, but also to reflect the communities we serve. We are dedicated to employing and retaining a diverse and inclusive workforce at all levels of the organization to not only ensure that different backgrounds and perspectives are being heard and acted upon, but that our employees also feel understood, accepted and valued.

 

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avidity team 3 avidty team 2

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Company info
Website
Phone
858-401-7900
Location
10578 Science Center Drive
Suite 125
San Diego
California
92121
US

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