(Senior) Research Associate T Cell Genome Editing

Location
Amsterdam
Posted
Oct 18, 2021
Required Education
Associate Degree
Position Type
Full time

Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the paradigm of treatment for solid cancers. Our mission is to provide cancer patients with T cell therapies targeting mutated proteins called neo-antigens, which are present on cancer cells as a consequence of DNA mutations. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.

For our R&D department in Amsterdam, we are seeking a highly motivated individual to join our T cell engineering research team as a (Senior) Research Associate. The individual will embrace state-of-the-art genome editing tools to enhance the potency and clinical efficacy of neo-antigen–based T cell therapies.

Responsibilities include, but are not limited to:

  • Performing experimental studies in the area of T cell cancer immunotherapy under the supervision of senior research staff, with a strong focus on the functional enhancement of T cells utilizing genome editing tools.
  • Collaborating with the broader R&D team including scientists, research associates and internship students.
  • Presenting obtained results in internal work discussions.
  • Documenting experimental results in electronic laboratory journal and data reports.
  • Completion of general tasks relating to laboratory operations, such as storage of incoming shipments, aliquoting of reagents and database maintenance for cryogenic storage.
  • Other duties as assigned.

Requirements:

  • Bachelor or Master’s degree in Biomedical Sciences or a related field. Candidates with at least 5 years of relevant work experience may be eligible for a position as a Senior Research Associate (at the company’s discretion).
  • Experience with primary T cell culture, phenotypic and functional evaluation of T cells by flow cytometry, genetic modification of primary T cells and cell lines (viral transduction, CRISPR/Cas9 etc) is strongly preferred.
  • Additional training in molecular biology (molecular cloning, RT-qPCR etc), cancer biology, next-generation sequencing, or functional genetic screening is a plus.
  • Excellent organizational skills, a strong sense of urgency with regards to work duties and the ability to deliver results based on challenging timelines.
  • Strong verbal and written communication skills in English.
  • Comfortable in a fast-paced growing company environment and able to adjust workload based upon changing priorities.
  • We are seeking a person who will lead by example and is a self-motivated team player with strong interpersonal skills.

We offer the opportunity to join a highly dynamic growth-stage biotech company. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide a unique opportunity to be a major contributor to the success of a well-positioned, well-financed growth-stage biotechnology company.