Research Scientist, Antibody Discovery

94608, Emeryville
Oct 13, 2021
Required Education
Position Type
Full time

The Research Scientist position reports to the Director, Cell Biology supporting Ligand’s OmniAb Technology platform, and is responsible for guiding OmniAb antibody discovery campaigns from immunization to the best possible panel of therapeutic candidate antibodies.  The position calls for strong technical skills and hands-on experience in antibody discovery, molecular biology, and assay development. Additionally, the role will involve coordinating experiments across a variety of internal and external projects; so, strong communication skills and a collaborative nature is a must.  

The OmniAb group at Ligand consists of dynamic and innovative scientists that employ a variety of novel platforms to support our partners in discovering the best antibodies possible for their therapeutic applications. At the core of OmniAb is the ability to engineer animals to generate affinity matured human sequence antibodies for use in conventional and novel formats. We leverage our proprietary animals with state-of-the-art technology in antigen design, immunization methods and high-throughput single B cell screening to facilitate discovery of best-in-class antibodies. We are looking for accomplished team players who are enthusiastic to contribute to the technological frontier of antibody discovery, and passionate in their desire to collaborate with partners to develop next generation therapeutics. See for more details about the exciting science being performed at Ligand.

About Ligand * Ligand is a biopharmaceutical company focused on developing or acquiring technologies that help pharmaceutical companies discover and develop medicines. Ligand employs research technologies such as antibody discovery technologies, ion channel discovery technology, Pseudomonas fluorescens protein expression technology, formulation science and liver targeted pro-drug technologies to assist companies in their work toward securing prescription drug and biologic approvals.

Experience and Skills

  • Design and execute antibody discovery workflows
  • Guide therapeutic antibody discovery efforts for partner and/or internal projects
  • Preparation and communication of experimental data reports for partner and internal antibody discovery programs
  • Collaborate with internal team members on lab operations and work flow

Non-essential Role Responsibilities Include

  • Presentations at major antibody conferences
  • Mentor research associates
  • Other duties as required

Minimum Requirements

  • PhD with 2+ yrs relevant experience
  • BS or MS in Biology or equivalent, with extensive industry experience (7-12 years) including antibody discovery
  • Experience in mammalian cell culture is required
  • Experience with techniques for antibody characterization such as ELISA, FACS and cellular assays is required
  • Experience in molecular biology is preferred
  • Experience in antibody cloning and expression is preferred
  • Experience in project management is preferred
  • Eagerness to learn new methods and apply knowledge to a steady stream of new projects with distinct goals
  • Must demonstrate well-developed communication, record keeping, organizational skills, and the ability to work in a team environment


  • The company offers competitive benefits including medical, dental, vision, Short/Long term disability and life insurance, as well as 401(k) match, Stock Options, Bonus, and paid time leave

Additional Information

  • All new hires are required to go through a background and reference check
  • Ligand is an EEO/AA/Disability/Vets employer
  • Ligand celebrates the diversity of life and welcomes all individuals to apply
  • Must be legally authorized to work in the US without sponsorship