Research Scientist (Chemist)
Arvinas is a clinical-stage biopharmaceutical company leading the way in targeted protein degradation therapeutics. Arvinas is the first company to focus solely on protein degradation and its platform technology is the most advanced in the field. Since its founding in 2013, Arvinas’ PROTAC® Discovery Engine has been driving the most significant breakthroughs in the industry. Arvinas’ pipeline encompasses a range of validated and undruggable targets in oncology, immuno-oncology, and neuroscience. This includes two clinical-stage programs: ARV-110, which is being developed as a potential treatment for men with late-line metastatic castrate-resistant prostate cancer, and ARV-471, which is being developed as a potential treatment for patients with breast cancer.
#TeamArvinas is made up of more than 200 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and purpose – to improve the well-being of patients and families impacted by the devastating diseases Arvinas is working to treat. It’s an exciting time to be in drug development and it’s an exciting time to be at Arvinas. But don’t just take our word for it – here’s what Arvinas employees are saying. For more information, please visit www.arvinas.com.
Research Scientist (Chemist)
Location: New Haven, CT
Name of employer: Arvinas, Inc.
Serve as member of the development team and execute formulation strategy for drug candidates; work with team to execute exploratory research and development of formulations for pre-clinical animal and clinical drug discovery, pharmacology, pharmacokinetic, and toxicology studies; manage contract development and manufacturing organizations (CDMOs); support animal groups in preparing dosing solutions and designing vehicles for Biopharmaceutical Classification System II/IV compounds; prepare manufacturing batch records; prepare requests-for-proposals; select vendors; monitor activities/emergent data of/from formulation development and manufacturing organizations; assemble/evaluate preclinical and clinical pharmaceutical study data and assist with drafting relevant sections of regulatory documents (e.g., INDs and NDAs).
Requires M.S. in a Pharmaceutical Science field (Pharmacology, Pharmaceutical Chemistry, Pharmaceutics, Pharmacognosy) and 3 years of post-graduate experience in the job offered or in industrial drug characterization and development OR foreign equivalent/combination of education & experience. Requires experience with 1) hands-on laboratory experience with BCS II/IV compounds and their formulations; 2) processing and analytical methods used for amorphous formulations; 3) writing and maintaining of quality control (QC) and standard operating procedure (SOP) documentation; 4) presenting complex information to scientists from other disciplines; 5) supervising subordinates. Must have familiarity with: 1) cGMP regulations, 2) USP procedures, 3) Microsoft Office, & HPLC systems. Must be able to present at least 2 publications sponsored by the American Chemical Society or American Association of Pharmaceutical Science (AAPS) and have a history of presenting at AAPS conferences.
Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com
Arvinas is an Equal Opportunity employer