Amgen

Scientist - Medicinal Chemistry

Employer
Amgen
Location
Thousand Oaks, CA
Posted
Oct 09, 2021
Ref
R-127124
Required Education
Associate Degree
Position Type
Full time

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of. Join us.

SCIENTIST MEDICINAL CHEMISTRY

LIVE

WHAT YOU WILL DO

Lets do this. Lets change the world. In this vital role you will be part of a fast-paced, integrated and interactive Selection and Modality Engineering group with responsibilities including (but not limited to) the discovery, design, synthesis, and purification of novel compounds for potential clinical drug development. This will include the opportunity to work within Amgens RNA-based therapeutics platform, which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging siRNA modality.

  • The Scientist will interact directly with researchers in high-throughput small molecule and DNA-encoded library screening to identify novel surface receptor ligands and lead efforts to optimize these hits for functional delivery of oligonucleotides.
  • Additional responsibilities include but not limited to: devising and implementing creative scientific strategies to address synthetic and medicinal chemistry issues through conducting laboratory experiments, working closely with other researchers to influence team direction and advance programs, communicating progress and strategy in various forums, and preparing technical documents.
  • The Scientist will serve as a scientific resource to the department who will champion new technologies/ideas to enhance capabilities.
  • The Scientist may directly or indirectly manage research associates within a collaborative environment and be responsible for providing motivating professional development coaching within his/her group.

WIN

WHAT WE EXPECT OF YOU

We are all different, yet we all use our unique contributions to serve patients. The Medicinal Research professional we seek is a self-disciplined Scientist with these qualifications.

BASIC QUALIFICATIONS

  • Doctorate degree OR
  • Master's degree and 3 years of medicinal chemistry or pharmaceutical research experience OR
  • Bachelor's degree and 5 years of medicinal chemistry or pharmaceutical research experience

PREFERRED QUALIFICATIONS

  • Doctorate degree in chemistry specializing in organic synthesis
  • 3+ years of experience in medicinal chemistry
  • Experience participating on a team that has advanced compounds to clinical development
  • Track record of consistent and successful drug discovery accomplishments (e.g., patent inventorship, conference presentations, and peer-reviewed publications)
  • Deep understanding of synthetic, medicinal and chemistry concepts with high lab productivity
  • Demonstration of good lab practices, with particular attention to safety
  • Proficient skills in parallel synthesis and use of structure-based or other computer-aided design tools
  • Broad understanding of drug discovery disciplines (e.g., chemistry, biology, safety, PKDM, etc.)
  • Experience coaching others (internal or CRO)
  • Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

THRIVE

WHAT YOU CAN EXPECT OF US

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

APPLY NOW

FOR A CAREER THAT DEFIES IMAGINATION

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

CAREERS.AMGEN.COM


Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.