Director, Computational Sciences

Cambridge, MA
Oct 08, 2021
Required Education
Bachelors Degree
Position Type
Full time

Why Join Intellia? 

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. 

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. 

We want all of our people to go beyond what is possible. We aren’t constrained by typical end rails, and we aren’t out to just “treat” people. We’re all in this for something more. We’re driven to cure and motivated for change. Just imagine the possibilities of what we can do together.   

How you will Achieve More with Intellia:

Intellia is searching for an experienced Director of Computational Sciences to support and build the design and implementation of computational tools and analysis to support the development of genome editing-based therapeutics.  In this essential role, you will lead a team of computational scientists working cross-functionally to support research and development programs.  This is a highly visible leadership position interacting across R&D as well as engage in regulatory interactions.

  • Support the development of genome editing based therapeutics through the design and implementation of computational tools and analyses

  • Serve as functional representative on cell therapy and in vivo programs teams responsible for the execution of on- and off-target data packages to support development candidate nomination through regulatory filing

  • Grow and maintain a high-performing team including hiring, training, staff assignment, coaching, mentoring, developing relevant metrics, and performance management.

  • Maintain a culture focused on collaboration, innovation, teamwork, and communication

  • Manage, lead, and mentor a team of talented/motivated computational scientists

  • Function as subject matter expert in the Computational Biology group and the wider organization

  • Utilize computational methods to analyze, integrate and visualize genomic data

  • Lead the build-out of novel bioinformatic pipelines to process large amounts of NGS/screening data and apply or develop data-mining tools to mine large data sets

  • Leverage internal/external data with machine learning and AI to develop and improve prediction algorithms

  • Leverage -omic data sets, clinical data, and computational approaches to support and guide clinical development programs as well as to enable ongoing target discovery efforts

  • Partner with research leads to assess computational needs across all functions including chemistry, gene editing, pharmacology, immunology, and disease biology

  • Implement data integrity and code review processes

About You:

  • BS/MS in Bioinformatics, Computer Science or related field with 15 years of industry experience OR Ph.D. in Bioinformatics, Computer Science or related field with 10 years of industry experience

  • Demonstrated ability to write code in one of the following programming languages C/C++, Python, R

  • Familiar with Linux and shell scripting/bash

  • Familiar with cloud-based computing environments, preferably Amazon Web Service

  • Familiar with popular bioinformatics databases and tools

  • Experience with databases is a plus

  • Experience with web development is a plus

Meet your future team:

You will lead a critical core function of talented, innovative, passionate computational scientists partnering with genomics, screening, software engineering, and automation to build custom solutions for data interpretation, visualization, and innovation.  We are accountable for enabling our programs in early research to reach development candidate nomination through regulatory filing and into clinical trials as well as support our internal platform optimization efforts in both the in vivo and cell therapy space.

In this key leadership role, you will report directly to the Senior Director, AEGIS (Automation, Engineering, Genomics, Informatics, and Screening), who instills a culture of teamwork, respect, inclusion, collaboration, and communication ensuring that each team member strives to reach their professional and personal potential.


Covid-19 Vaccination Policy: Effective Monday, January 3, 2022, all Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.