Associate Research Scientist

Oct 08, 2021
Required Education
Bachelors Degree
Position Type

This position is a combination of remote and onsite work.
Important Note: Flow Cytometry experience is required to be considered for the position.
Job Description
The Associate Scientist in the analytical development group will plan and execute experiments to interrogate the phenotype and function of gene-modified T cell drug products in partnership with senior staff. This role will be responsible for participating in laboratory experiments to develop new and manage existing flow cytometry/next generation flow cytometry methods intended for release testing and/or characterization. The Associate Scientist will be a member of matrix team within the analytical development group participating in the development, transfer and management of flow cytometry/next generation flow cytometry methods. Additionally, the Associate Scientist will be experienced in flow cytometry, next generation cell interrogation techniques and immunology concepts.
Key Responsibilities
• Lab-based role responsible for planning and executing method development, qualification and transfer of release or characterization methods for clinical-stage CAR-T/TCR programs in partnership with senior staff.
• Troubleshoots and solves technical problems pertaining to flow cytometry methods with internal QC and/or operations teams.
• Regularly presents findings and communicates with the team and other internal/external collaborators, as needed.
• Participate in investigations and troubleshooting flow cytometry analytical methods.
• Maintain a thoroughly documented ELN.
• Draft new and/or modify protocols, SOPs and technical reports in partnership with senior staff.
• Ability to handle multiple tasks, prioritize effectively and work well in highly matrixed team environment with flexibility to navigate dynamic project goals.
Qualifications & Experience
• Minimum Bachelors degree (BA or BS) with 4+ years of experience, Masters Degree (MA or MS) with 2+ years of experience, or doctorate (PhD) in Immunology, Cell Biology, Cancer Biology or related field.
• Familiarity with molecular and cellular immunology concepts and techniques.
• Experience with flow cytometry including in vitro T cell functional assays and tissue culture.
• Experience with flow cytometry analysis software (FlowJo, FACSDiva, FSCExpress, etc.) as well as statistical software (JMP, R, Spotfire, Prism, etc.).
• Experience with BD Flow Cytometer instrumentation (FACSCanto, Fortessa, Symphony, Aria, etc.)
• Proficiency in assay development and qualification desired.
• Demonstrated ability to work effectively in cross-functional teams.